Four kinds of dialkylaminoethyl ether and thioether derivatives of β-tetralylphen-ylmethane were prepared for use in pharmacological test. None of these compounds offered better activities as compared to diphenhydramin hydrochloride in the point of toxicity, analgesia, etc., but their local anesthetic activity was quite marked, showing stronger action than that of cocaine. However, local irritation was also observed at the same time.
