ステロイドホルモンと血清蛋白の関係 (第5報)

蛋白結合ステロイドの物理化学的性質 (2)

抄録

Combination of steroidal hormones with bovine serum albumin or globulin was examined. In the combination of steroids with bovine serum globulin, protein turbidity and the amount of combined steroid are in approximately linear relationship but in combination with serum albumin, this relationship is more like adsorption curve. The wave height of the 2nd wave of proteins in polarography in ammonium chlorideammonia buffer containing cobaltous chloride shows negative correlation to some extent with the amount of combined steroid. This combination is partially undertaken by -CO-NH-, -NH₂, and -COOH in the protein molecule and the individual amino acid forming the serum albumin and globulin, and -S-S- or -SH in the protein molecule do not take part in this combination with steroids.