1958 Volume 78 Issue 9 Pages 1045-1049
Effect of substituent on the equilibrium of benzylidene-INAH derivatives in equeous solution was examined and it was clarified that the logarithm of equilibrium constant (K0) of free bases and substituent constant were in linear relationship. The value Ks, which represents basicity of the azomethine group, has no connection with a substituent but is related to the change of mesomerism due to addition of a proton to the pyridine portion. Calculation of keinetic values showed that satisfaction of the Hammett law was due to the constancy of entropy difference.
