アルカミン類の研究 (第11報)
L-threo-ならびにL-erythro-1-p-Nitrophenyl-2-benzamido-3-benzoyloxypropan-1-olと塩化チオニルとの反応について
1959 年 79 巻 7 号 p. 942-945
詳細
1959 年 79 巻 7 号 p. 942-945
Jacob obtained D-threo-1-p-nitrophenyl-1-chloro-2-dichloroacetamido-3-benzoyloxypropane by treatment of L-erythro-1-p-nitrophenyl-2-dichloroacetamido-3-benzoyloxypropan-1-ol with thionyl chloride, and this shows that an inversion had taken place at the C-N center in this reaction. Treatment of L-threo- and L-erythro-1-p-nitrophenyl-2--benzamido-3-benzoyloxypropan-1-ol with thionyl chloride in pyridine afforded L-threo-1-p-nitrophenyl-1-chloro-2-benzamido-3-benzoyloxypropane in both cases and the inversion at C-N center did not take place in this reaction.
