アルカミン類の研究 (第12報)
L-threo- ならびに L-erythro-2-Phenyl-4-(α-hydroxy-p-nitrobenzyl)-2-oxazolineの合成ならびに塩化チオニルとの反応について
1959 年 79 巻 7 号 p. 945-949
詳細
1959 年 79 巻 7 号 p. 945-949
L-threo-1-p-Nitrophenyl-1-benzoyloxy-2-amino-3-chloropropane produced L-threo-and L-erythro-2-phenyl-4-(a-hydroxyp-nitrobenzyl)-2-oxazoline whose treatment with thionyl chloride afforded L-threo-1-p-nitrophenyl-1-benzoyloxy-2-amino-3-chloropro-pane hydrochloride from L-threo-oxazoline, and its D-threo compound from L-erythro-oxazoline. This shows that inversion of the C-N center took place only in L-erythro-oxazoline and indicates that it would be possible to convert the L-threo base to D-threo base by combianation of the above reaction with the reaction in which inversion of C-O center is effected, which was described in a previous paper.
