In order to fortify the antimicrobial activity of 2-methoxymethyl-5-nitrofuran (I), which is known as the antifungal agent, the methoxyl group was substituted with alkoxyl group. The 2-alkoxymethyl compounds so formed showed antifungal activity against Trichophyton and Microsporum spp., and the compounds with alkyl group of C3H7 to C8H17 also showed strong antibacterial activity against H37Rv strain of tubercle bacilli.
