1960 年 80 巻 3 号 p. 349-353
Oxidation of 2, 3-dimethylpyrazine with potassium permanganate afforded 3-methylpyrazine-2-carboxylic acid but not pyrazine-2, 3-dicarboxylic acid. Further permanganate oxidation of 3-methylpyrazine-2-carboxylic acid afforded the 2, 3-dicarboxylic acid, though in an extremely poor yield. 3-Methylpyrazine-2-carboxylic acid was also obtained by electrolytic oxidation in the presence of potassium permanganate. Copper, nickel and lead were used as the electrode. There was no great increase in the yield in spite of changes in electrolytic conditions such as the kind of electrode used, current density, reaction of the solution, and temperature.