抄録
Digestive enzyme preparations like pancreatin and diastase are generally sensitive to gastric juice and their major portion is destroyed on contact with gastric juice. In order to obtain acid-stable digestive enzyme, which would fully exhibit its digestive power in gastric juice, approximately 170 strains of Aspcrgillus sp. were isolated from natural source, submitted to wheat bran culture, and potency assay was carried out on their culture extract. One of the strain isolated, belonging to Aspergillus oryzae morphologically, had stronger proteinolytic activity at pH 3-6 than Aspergillus niger and was named Aspergillus oryzae TPR-18.