YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
耐酸性消化酵素剤の研究 (第1報)
Aspergillus属の糸状菌より得られる耐酸性消化酵素について
野上 寿岩崎 由雄波止 保田中 一郎柳澤 崇明澤田 二郎
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1960 年 80 巻 3 号 p. 365-370

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Digestive enzyme preparations like pancreatin and diastase are generally sensitive to gastric juice and their major portion is destroyed on contact with gastric juice. In order to obtain acid-stable digestive enzyme, which would fully exhibit its digestive power in gastric juice, approximately 170 strains of Aspcrgillus sp. were isolated from natural source, submitted to wheat bran culture, and potency assay was carried out on their culture extract. One of the strain isolated, belonging to Aspergillus oryzae morphologically, had stronger proteinolytic activity at pH 3-6 than Aspergillus niger and was named Aspergillus oryzae TPR-18.
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© by the PHARMACEUTICAL SOCIETY OF JAPAN
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