薬剤の安定性に関する研究 (第1報)
ベンゾサイアダイアジン系化合物の安定性 その1 4-Amino-6-chloro-m-benzenedisulfonamideの定量法
1961 年 81 巻 5 号 p. 783-784
詳細
1961 年 81 巻 5 号 p. 783-784
Photometric method for the determination of 4-amino-6-chloro-m-benzenedisulfonamide, one of the hydrolysis products of benzothiadiazinines, was developed. The disulfonamide is determined by reaction with 4N hydrochloric acid and nitrous acid at 30°, and coupling of the diazonium compound formed with the Tsudareagent. The resulting red color which is read through a filter (535mμ) is linear in absorbance to the concentration of disulfonamide.
