2-置換レピジンとベンズアルデヒドおよびp-ジメチルアミノベンズアルデヒドとの反応

抄録

In order to synthesize 4-styrylquinoline derivatives possessing the substituent at 2-position of quinoline ring, condensation of 2-substituted lepidine and Benzaldehyde or p-dimethylaminobenzaldehyde were examined. Zinc chloride, acetic anhydride and potassium alcoholate were employed as the condensing agents. This method was mostly not befitting for the syntheses of 2-substituted 4-styrylquinoline derivatives since the substitution at 2-position affected greatly the activity of methyl group at 4-position.