抄録
When α-picoline 1-oxide and phenacyl bromide are mixed under cooling and the solidified crystals are washed with anhydrous ether and benzene, O-phenacyl compound (I), m.p. 70°, of α-picoline 1-oxide is obtained. Basification of this product (I) with sodium carbonate gives phenylglyoxal easily in ca. 50% yield. If a solvent is used and the mixture is heated, this yield becomes lower. The use of acetone produces α-picoline 1-oxide 1/2hydrobromide (II), m.p. 142°. Reaction of α-picoline 1-oxide and α-bromoacetone in benzene gave pyruvic aldehyde in 26% yield.
