抄録
In continuation of the previous work, five kinds of mixed samples of antifebrile-analgesics were prepared, including aminopyrine and antipyrine, and detection of their componental principles from the mass spectrum of mixtures was confirmed.
Mass spectra were also measured with commercial products of powders, granules, tablets, sugar-coated tablets, and ampules of mixed drugs and it was found that identification of each component was possible in a short time with a small amount of the sample by measuring their mass spectrum. Examinations were also made on the fragment peak and pattern coefficient of various preparations of commercial cold cures and facile identification of components was found possible, not only with aspyrine, acetophenetidine, caffeine, antipyrine, and aminopyrine but also with chlorophenilamine, cyclobarbital, barbital, and dihydrocodeine. Further studies are now being made for the quantitative estimation of these components and accumulation of mass spectral data of other kinds of pharmaceuticals.
