Studies on Fungicides. XII. Synthesis and Antifungal Activity of Halogen Substituted Phenyl Pyrazolone Derivatives

Abstract

Phenylpyrazolone derivatives with various halogen substituents were synthesized and relationship between their structure and antifungal activity was examined, using Corticium sasakii. Antifungal activity tended to become weaker in the order of phenylhydrazines, β-acetylphenylhydrazines, phenylhydrazones, and phenylpyrazolones, and with the increasing number of halogens substituted.