抄録
Acid-catalyzed reaction of β-D-glucopyranosiduronic acid was examined and a linear relation was found between the logarithm of the first-order rate coefficient and Hammet's acidity function, the slope of the line being approximately 1. This relationship agrees with the reaction mechanism known as the A-1 reaction among the Zucker-Hammet hypotheses, although there was a difference in the slope of the line according to various acids. The straight line obtained on addition of a salt to the acid solution agreed approximately with the straight line obtained without the addition of a salt. Rate of acid hydrolysis in heavy water solution was greater than that in aqueous solution. These results suggest that the acid-catalyzed reaction of β-D-glucopyranosiduronic acid has the same reaction mechanism as that of A-1 reaction proposed for glucopyranosides.
