YAKUGAKU ZASSHI
Online ISSN : 1347-5231
Print ISSN : 0031-6903
ISSN-L : 0031-6903
結核菌に対する化学療法剤の研究(第20報) : Orcilaldehyde, β-Orcilaldehyde, Atranol およびDivaraldehyde誘導体の合成ならびに抗菌作用について
藤川 福二郎中村 泰三西牧 敏子白井 邦子松井 清横山 年子内藤 益一津久間 俊次
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1968 年 88 巻 10 号 p. 1264-1269

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A total of 62 kinds of compounds to be derived from lichen components by decomposition were synthesized. These included 25 kinds of orcilaldehyde derivatives, 8 kinds of β-orcilaladehyde derivatives, 7 kinds of atranol derivatives, and 22 kinds of divaraldehyde derivatives. Antibacterial action of these compounds were tested with human type tubercle bacilli, the sensitive H37RvS strain and the resistat H37RvR strain which is resistant to over 300 μg/ml of streptomycin, 50 μg/ml of p-aminosalicylic acid, and 50 μg/ml of INAH. None of the compounds tested had antibacterial action against these two strains.

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