Abstract
Ethynylation of 2-furyl (para-substituted phenyl) ketones (Ia-d), 2-(5-nitrofuryl) (para-substituted phenyl) ketones (IIIa, b), p, p'-disubstituted benzophenones (Va, b and VIIa-c), and 2-thienyl phenyl ketone (IXa) with lithium acetylide or lithium acetylideethylenediamine afforded the corresponding ethynylcarbinol (IIa-d, IVa, b, VIa, b, VIIIa-c, and Xa) in 30-84% yield. Isolation of the corresponding ethynylcarbinols (IVc and IVd) was not successful in the case of 2-(5-nitrofuryl) p-chlorophenyl ketone (IIIc) and 2-(5-nitrofuryl) p-bromophenyl ketone (IIId).
