9位置換アデニンおよびその1位メチル誘導体の合成
1969 年 89 巻 4 号 p. 591-594
詳細
1969 年 89 巻 4 号 p. 591-594
9-Substituted adenines (VI) were synthesized with high yield from 4-amimo-5-nitro-6-substituted pyrimidines (III) under conditions that reduction of nitro group and cyclization was performed on a single process using hydrosulfite as the reducing agent. The overall yield from 4, 6-dichloro-5 -nitropyrimidine (I) was about 25-51%. 9-Ethyl-1-methyladenine and 9-benzyl-1-methyladenine were synthesized in addition.
