抄録
In order to examine the reductive cleavage of aminoxazoles, benzyl 4- and 5-oxazole-carbamates (I and II) were synthesized, and then submitted to catalytic reduction. When using palladium-carbon catalyst in ethanol, I was converted to a brown resin, but II afforded acylaminonitriles (IV) by the conversion of 5-aminoxazoles (III) formed. I and II were converted to acetamidoxazoles (V and VI) when using palladium-carbon catalyst in acetic anhydride. V and VI were easily converted to the corresponding ethylidenebisamides (VII) and ethylenebisamides (VIII) by ring fission when using platinum oxide in acetic acid. V was recovered but, with the exception of 2, 4-dimethylated VI (VIa), VI gave VIII when using palladium-carbon catalyst in ethanol.
