1971 年 91 巻 8 号 p. 804-810
Alkylthiochalcones (IV-LIV) were synthesized by the condensation of alkylthioacetophenones (I-III) with aromatic aldehydes for the purpose of screening their antibacterial activity in vitro. Of these chalcone derivatives tested, 18 compounds (IV, VI, XII, XIII, XVI, XIX, XX, XXII, XXIII, XXVIII, XXX, XXXI, XXXII, XXXVI, XXXVII, XXXIX, IL, and LIII) showed a relatively intense antibacterial activity against Bacills subtilis NRRL, and VI was also effective against Escherichia coli O-55. XXXVIII revealed antibacterial action only against Staphylococcus aureus 209 P.