Abstract
The tritium compound, 2-hydroxyestra-1, 3, 5(10)-trien-17β-ol[6, 7-3H], was prepared by catalytic hydrogenation of 2-methoxyestra-1, 3, 5(10), 6-tetaen-17β-ol acetate (IV) with tritium gas and palladium on charcoal in dioxane, followed by deacetylation and demethylation. Radioactivity and purity measurements of the stored highly labeled compound are described. About 99% of the isotopes in the labeled compound (VII) was found to be located at C6-and C7-positions of the molecule.
