Author's Organization：Faculty of Pharmaceutical Sciences, University of Tokyo Faculty of Pharmaceutical Sciences, University of Tokyo Faculty of Pharmaceutical Sciences, University of Tokyo
Optically active (-)-bisdehydroestrone methyl ether (V) was synthesized by two methods ; one is synthesis of (-)-V from optically pure S-(-)-II, and the other is the asymmetric cyclization of triketone (X) with L-proline pyrrolidide enamine method.
