抄録
5-Hydroxy-6-(4-methoxybenzyl)-4, 5-dimethyl-1-(3-methyl-2-butenyl) piperidin-2-one (15) was synthesized and subjected to Grewe cyclization, in which the product obtained was not identified. During the synthesis of this compound (15), the improved sequence for 1-benzyl-6-(4-methoxybenzyl)-4-methoxycarbonylpiperidine-2, 5-dione (23) was found.