Biological Sciences in Space
Online ISSN : 1349-967X
Print ISSN : 0914-9201
ISSN-L : 0914-9201
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Volume 7, Issue 1
Displaying 1-4 of 4 articles from this issue
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Review
  • The Activation of T Lymphocytes in Space - An Overview
    Augusto Cogoli
    Article type: Others
    Subject area: Others
    1993 Volume 7 Issue 1 Pages 1-7
    Published: 1993
    Released on J-STAGE: April 08, 2005
    DOIhttps://doi.org/10.2187/bss.7.1
    JOURNAL FREE ACCESS
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    T lymphocytes are one of the rare human cell types that can be triggered in-vitro to differentiate into activated cells. Some aspects or the transformation are still unknown and object of extensive research in several laboratories. Experiments conducted in microgravity showed that the T lymphocyte-monocyte system is extremely sensitive to changes of the gravitational environment. Microgravity can be used as a tool to understand certain aspects of the mechanism of cell proliferation, genetic expression and secretion of specific products.
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Original Paper
  • Enhancing Effect of Hypergravity on Development of Cardiac and Skeletal Muscles of Chick Embryos
    Tsuneo Sato, Wataru Shirai, Masakatsu Shioya, Kohtaro Kawashima, Hiroy ...
    Article type: Others
    Subject area: Others
    1993 Volume 7 Issue 1 Pages 9-12
    Published: 1993
    Released on J-STAGE: April 08, 2005
    DOIhttps://doi.org/10.2187/bss.7.9
    JOURNAL FREE ACCESS
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    Fertilized eggs of White Leghorn chickens were incubated for 11 days at 37°C in normal condition and then for 7 days under hypergravity (2G) induced by centrifugation. Then the morphologies of muscles isolated from their heart ventricle and femur were examined. The cardiac and skeletal muscle cells of the 2G-group were more densely packed and regularly organized than those of the control group. Collagen and lattice fibers were also more abundant in stroma of the 2G-group. Electron microscopical studies showed that after hypergravity treatment, muscle cells contained a larger number of myofibrils forming larger bundles with clear electron dense Z-bands in the cytoplasm. These results show that hypergravity enhances the development of muscle cells.
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