The time courses of the phosphorus turnover of the nodular and ascites hepatoma and of the liver were investigated on the inorganic P, acid soluble organic P, lipid P, protein P, RNA-P and DNA-P fractionated by Schmidt-Thannhauser′s method, and on the IP, Co-P, Lab-P and St-P of the ATP and ADP, Pro-P, Ad-A, G-1-P, G-6-P, G-P-A, and P-G-A isolated by Sacks′ method.
The curve for the time course of the r. s. a. of BSIP dropped along the exponential curve C=C₁e^-k1t1÷C₂e^-k2t2. The acid soluble organic P and the lipid P of the tumor showed lower turnover than that of the liver, but DNA-P showed somewhat higher.
The turnover of the acid soluble P-compounds of the tumor tissues isolated by Sacks′ method was lower than that of the liver, and ranged in the following order: IP, Lab-P, G-1-P, Co-P, G-6-P, P-G-A, Ad-A, St-P, G-P-A and Pro-P.
The precursor of the phosphate of the Lab-P of ATP and ADP and of G-1-P seemed to be BSIP.

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We investigated the phosphorus turnover of the serum P and of acid soluble phosphorus in Yoshida sarcoma on the 7th day after the transplantation with the aid of P³².
The curve for the time course of the r.s.a. of the serum P dropped along the fomula C=C₁e^-k₁t₁+C₂e^-k₂t₂.
The specific activities of the phosphorus compounds 1 hour after the administration ranged in the following order: inorganic P, labile P of ATP and ADP, glucose-1-phosphate, phosphoglyceric acid, glucose-6-phosphate, adenylic acid and propanediol phosphate.
The precursor of the labile P of ATP and ADP and of glucose-1-phosphate seemed to be the serum inorganic phosphorus.
The r.s.a. of the phosphoglyceric acid of this tumor was relatively higher than that of another tumor.
Turnover of glucose-6-phosphate, adenylic acid, stable P of the ATP and ADP and of coenzyme P were roughly the same.

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