The Annual of Animal Psychology
Online ISSN : 1883-6283
Print ISSN : 0003-5130
ISSN-L : 0003-5130
Volume 16, Issue 2
Displaying 1-8 of 8 articles from this issue
  • TSUNEO IWASAKI, YASUO HASEGAWA, SHINKURO IWAHARA
    1966 Volume 16 Issue 2 Pages 75-85
    Published: December 25, 1966
    Released on J-STAGE: January 29, 2010
    JOURNAL FREE ACCESS
    Effects of two tranquilizers (CPZ, and homofenazine) upon shock-motivated behavior were studied as a function of the dose level (saline, 1, 2, 4, and 8 mg/kg, i. p.) and time after injection (0, 15, 30, 60, and 120 min.) with male rats satiated with food and water. CPZ was found to retard both starting and running time as an increase in dose level, and the same motor effect was maximal around 30 min. after injection under each dosage.
    On the other hand, no obvious dose-, nor time-response relationships were observed with the homofenazine-injected rats with respect to running time. Starting time was only slightly depressed by 8 mg/kg of homofenazine, and the time-response relationship in terms of starting time was not significant. However, conditioned avoidance response without electric shock was found to be depressed by homofenazine as an increasing function of dosage level. Thus it was hypothesized that the ataxic effect of homofenazine or the drug in general is a function of arousal level of the drugged animal.
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  • Modern research trends Vol. 1, 2 New York : Academic Press, 1965, pp. 595.
    [in Japanese]
    1966 Volume 16 Issue 2 Pages 86
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
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  • TAKASHI OGAWA
    1966 Volume 16 Issue 2 Pages 87-102
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
    Pigeons were trained with only one eye open to respond to one color stimulus and stimulus generalizations with both eyes open and with either eye open were tested in extinction trials. Generalization gradients along a spectral continuum were no differences between them except the rates of responding. Following conditional training in which appropriate responding depended on which eye was covered, generalization curves showed a bimodal shape which was made by the maximum rates of responding for two training stimuli, not only for both eyes open, but also for either eye open except the rates of responding.
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  • I. Effects of Chlorpromazine on Operant Responses and Irrelevant Responses
    TAKASHIGE IWAMOTO, YOSHITAKA UMEOKA
    1966 Volume 16 Issue 2 Pages 103-116
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
    In the free responding situation in operant conditioning, various reinforcement schedules have been used for the partial reinforcement training. Differential reinforcement of low rates (DRL) schedule is one such and is defined as follows : under this schedule, only operant responses that terminated within inter-response times (IRT) equal or longer than a given time are reinforced. In general, the procedures of partial reinforcement are classified into two major types. In one of them, the condition of reinforcement is depended upon the passed time after reinforced responses, while in another type it is depended upon the number of operant responses after reinforced responses. Although the DRL schedule should be considered to belong to the former since the reinforcible condition has a critical relation to the passed time after operant responses, it is a unique procedure in that the initiator of reinforcement is started with every operant response and the reinforcible condition is heavily dependent upon the S's operant responses.
    The present series of studies was carried out to investigate how the mechanism for inhibition of operant responses under the DRL training was formed and how it was modified under treatments of psychotropic drugs, observing operant responses and various behaviors deemed apparently irrelevant to the particular reinforcement schedule used.
    In the experiment reported here, the effects of chlorpromazine (CPZ) on the development and the modification of the operant responses and some of the irrelevant responses in the DRL training were examined using 16 male albino rats of Wister strain as experimental subjects.
    Under the DRL schedule of 12 sec, the bar-pressing behavior of the S's was reinforced with a pellet (0.05 g) in a turntable exerciser (6, 7, 21) having a bar for the operant responses and a food tray connected to a food magazine through a vinyl chloride tube. This continued for 6 consecutive days, and the running behavior during the DRL schedule was observed simultaneously. The daily training session was terminated when each S obtained 72 food reinforcements. On 7 th day of the DRL training, the Ss were divided into two groups, the T group (N=8) and the O group (N=8). The Ss in the T group were administered CPZ intraperitoneally (2.0 mg/kg) in a physiological saline solution (10 cc/kg) 30 min prior to the training session on the day, whereas the Ss in the O group were administered only the physiological saline (10 cc/kg). Except for the administration of these drugs, the procedure used was the same as that in the previous days. The next day, each group was again sub-divided into two groups of equal size, the E groups (given CPZ) and the O groups (given saline). In this session, the training procedure was changed from 72 to only 12 reinforcements, and immediately afterwards the extinction session was introduced. The criterion for extinction was the non-occurrence of the bar-pressing for at least 5 min. Records of extinction were taken, however, at least 30 min after it had begun. Main measurements taken in this experiment were as follows : the required time in the daily training session; the number of total bar-pressing responses; the number of total bar-pressing responses/the number of total reinforced responses; the distributions of the IRT's; the amount of running activities. A summary of experimental procedure is shown in Table 1.
    The main findings were as follows. As the DRL training sessions progressed, the number of total bar-pressing responses and the number of required responses per reinforcement deceased gradually (Fig. 2), and the distributions of IRT classes were gradually changed to increments of reinforcible IRT's (Fig. 3).
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  • The Effects of the Self-Stimulation Technique and ECS Procedure
    BEN YAGI, NORITAKA MORIGUCHI
    1966 Volume 16 Issue 2 Pages 117-132
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
    A motor excitement is caused by the acute effect of Methamphetamine hydrochloride (philopon, MA-HCl), a typical psychic stimulant. But it is reported that the chronic administration of MA-HCl has a marked effect to produce a long-lasting decrease of spontaneous activity, some perpetual reduction of responsiveness to stimuli, as well as declined emotion and volition and the manic-depressive state (29, 34).
    On the other hand, it is known that animals stimulate their own brains through bipolar electrode implanted chronically in the hypothalamus and telencephalon at the very high rates for many hours to exhaustion and show no intrinsic satiation tendencies.
    Then we come to the question as to whether or not electrical positive rewards by the technique of self-stimulation have an effect that regains the responsive tendencies reduced to abulia and any remedial values upon abulia produced by the chronic administration of MA-HCl.
    EXPERIMENT I
    The purpose of the present experiment is to study how to change the level of responsiveness to receive intracranial electrical positive rewards when rats are under the state of inactivity produced by the chronic administration of MA-HCl.
    Methods : Out of 30 male albino rats performing constant rate of self-stimulation, were selected five rats, weighing about 250 gm., with implantation of a bipolar silver electrode in the medial part of anterior hypothalamus. A circuit was arranged so that the rat could stimulate its own brain with a sine wave current of 60 cycles for 1/2 sec. per one response by pressing a lever. Animals were injected subcutaneously a 6 mg (dissolved by 2 cc saline) /kg of MA-HCl once everyday for 35 days. They were allowed to press the lever 150, times each day but not for over a period of 18 minutes every fifth day before, . during and after the period of MA-HCl administration and the extinction testing of it was given for ten minutes twice each period. During the period of drug injection, self-stimulation was observed starting 90 minutes after the administration of the drug. After completion of the experiments, animals were sacrificed and their brains sectioned and examined microscopically to determine the exact location of the electrode tips.
    Results and discussion : At the beginning of the experiment, the suitable voltages of electrical self-stimulation were adjusted not to induce excessive excitement ; 1.5 v. for the rat A and B, 2.0 v..for the rat C and 2.5 v. for the rat D and E. From the fifteenth day of the injection period, however, almost all the rats showed the excessive excitements ; stupors, tetanic spasms and convulsive fits. To eliminate them the levels of voltage had to be decreased to 1.0 v. for the rats A and C and 0.5 v. for the rat B but not for the rats D and E. Though all the convulsions did not disappear, rats began to press the lever invariably after crouchings and convulsions which caused the decrease of the response rate as well as the increase of its oscillation as shown in Fig. 1 & 2. During and after the period of medication, resistance to extinction showed about one and half times higher rates of responding than before the period of injection. Response level does not fall off below the original level after the cessation of long term injection as shown in Fig. 1 & 2. Hypothalamic stimulations are interpreted to be effective to maintain the original level in responsiveness.
    EXPERIMENT II
    The response rate of self-stimulation never decreases even after chronic medication with methamphetamine as shown in the experiment 1. An electroconvulsive shock (ECS), on the other hand, is known to be therapeutically useful to a wide range of psychoses. Then we have a question whether or not ECS is also effective to increase responsiveness and activity. The purpose of this experiment is to investigate the effect of ECS upon the activity which is under the condition of abulia produced by chronic administration of MA-HCl.
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  • MICHIHIKO MATSUDA
    1966 Volume 16 Issue 2 Pages 133-139
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
    The purpose of this study was to investigate the effects of chlordiazepoxide on the switch-off behavior (SOB) motivated by hypothalamic stimulation in nine tame adult cats.
    Chlordiazepoxide (10mg/kg) was administrated by an intramuscular injection. The response latency of SOB was measured just before the administration of chlordiazepoxide, and 30 minutes, 1 hr, 2 hrs, 3 hrs, and 24 hrs after the administration.
    The results were followings :
    1. Grooming behavior appeared about 1 hr after the administration of chlordiazepoxide and continued for about 1 hr.
    2. The response latency of SOB began to lengthen at about 30 minutes or 1 hr after the administration of chlordiazepoxide, and was the longest at about 2 hrs after the administration. The latency of SOB at about 24 hr after the administration of chlordiazepoxide was as long as before the administration.
    3. From these observations, it is considered that the locus of actions of chlordiazepoxide in the brain was the hypothalamus. In some other studies, it was reported that the locus of actions of chlordiazepoxide in the brain might be the amygdala. This disagreement could be explained by the mechanism that the amygdala might regulate the emotional responses produced by the hypothalamus.
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  • [in Japanese]
    1966 Volume 16 Issue 2 Pages 140
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
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  • [in Japanese]
    1966 Volume 16 Issue 2 Pages 141-145
    Published: December 25, 1966
    Released on J-STAGE: October 14, 2009
    JOURNAL FREE ACCESS
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