The development of respiratory symptoms and diseases such as cough, sputum, wheezing, and asthma is affected by environmental factors such as air pollution, residential environments, and life style, and international comparative studies are useful for evaluating these factors. To investigate the association between the development of respiratory symptoms and environmental conditions, we carried out surveys of school children and their adult family members using ATS-DLD inquiry bills used in Japan in cooperation with Shenyang Medical College in Benxi in Liaoning in the eastern part of China where heavy chemical plants mainly iron plants have long flourished. In 1997,a survey of about 5,500 school children and their parents was performed to evaluate the association between the prevalence of respiratory symptoms and environmental factors in Benxi in Liaoning where iron production, steel production, and lime production have been prosperous. In addition, non-specific serum IgE antibody titers were determined in about 300 random samples. In Benxi, the amount of soot particle fall was about 20 times higher, and the amount of sulfur dioxide was about 8 times higher than that in the present Yokkaichi, showing a status similar to that in the worst air pollution period in Japan. The prevalence rates of all respiratory symptoms such as cough, sputum, and wheezing, excluding asthma, in school children was about 2〜3 times higher in Benxi than in the present Japan. As environmental conditions other than air pollution, 7 items were evaluated, but no marked influence of any factor could be found. The prevalence of respiratory symptoms increased under 3 environmental conditions (use of coal stoves, use of clay briquette stoves in the kitchen, and non-use or absence of ventilation fans), but no significant difference was observed. The incidence of high serum IgE levels was high in pollution areas, suggesting the influence of air pollution.
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