Journal of Intestinal Microbiology
Online ISSN : 1349-8363
Print ISSN : 1343-0882
ISSN-L : 1343-0882
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Volume 24, Issue 1
Displaying 1-1 of 1 articles from this issue
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Review
  • Effect of probiotics on Helicobacter pylori infection
    Shigeru KAMIYA
    2010 Volume 24 Issue 1 Pages 1-12
    Published: 2010
    Released on J-STAGE: February 27, 2010
    DOIhttps://doi.org/10.11209/jim.24.1
    JOURNAL FREE ACCESS
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    It has been reported that probiotic treatment is useful for Helicobacter pylori infection. In in vitro studies, probiotic bacteria including Lactobacillus, Bifidobacterium, Streptococcus, Clostridium and Saccharomyces inhibited adhesion and growth of H. pylori. In addition, various probiotic bacteria inhibited colonization of H. pylori in gastric mucosa in in vivo studies using germ-free mice, Mongolian gerbils etc. According to many clinical studies including meta-analysis, it has been shown that probiotic treatment decreases the number of H. pylori bacteria increases the eradication rate by inhibiting the proton-pump with antibiotics and prevents various side effects caused by eradication therapy. Use of probiotics, which are very safe for humans, is expected to assist with the eradication of H. pylori infection.
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