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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[in Japanese]

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[Objective] Importance of micronutrients is tended to be undervalued in comparison to that of the three major nutrients in nutritional management of the long term-hospitalized elderly. The aim of this prospective comparative study is to investigate influences of micronutrients enrichment on nutritional state and prevention of infection in the long term-hospitalized elderly.
[Methods] Fifty four hospitalized elderly were randomized to those who took micronutrients-enriched jelly prior to regular lunch meal (treated group), and those who did not (non-treated group). During 90 study days, blood biochemical analysis, nutritional assessment and observation of febrile event were performed.
[Results] Plasma levels of transthyretin (TTR) increased significantly in the treated group. A significant negative correlation between the plasma levels of TTR and cumulative frequency of febrile event during the 90-study days was found in the treated group, while this correlation was not observed in the nontreated group.
[Conclusion] In nutritional management of the long term-hospitalized elderly, it was suggested that micronutrients enrichment is important equally to the three major nutrients supply.

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[Objectives] The purpose of this feasibility study is to estimate the necessity of supplementing trace elements in healthy elderly subjects in order to prevent an insufficiency of such trace elements.
[Subjects and Methods] Twenty-two healthy elderly subjects (elderly group) and 29 of healthy young volunteers (young group) participated in this study. The results of blood biochemical examinations and the serum concentrations of trace elements (iron, copper, zinc, selenium, and manganese) were compared between both groups.
[Results] Zinc insufficiency was significantly higher in the elderly group and the zinc was found to be positively related with that of albumin. Regarding the others trace elements, no significant differences were observed in either group, although iron insufficiency was recognized with a high incidence, namely 23.5%. The serum level of all trace elements, except for copper, appeared to show a lower concentration in the elderly group.
[Conclusion] Zinc insufficiency was observed in the elderly subjects, particularly in association with the malnutrition status. The routine supplementation of trace elements in healthy elderly subjects is therefore not considered to be necessary. However, elderly subjects are considered to require nutrient support with trace elements at times of invasion, since such individuals are considered to be at risk for developing a trace-element deficiency.

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