Optical coherence tomography (OCT) is a noninvasive technique to obtain cross-sectional images of light scattering medium like living tissues. Doppler OCT has been developed to measure blood flow velocity in microvessels, while Fourier-domain OCT (FDOCT) has been invented as a high-speed substitute of time-domain OCT (TDOCT). They have been combined into a rapid visualization method of microvessels called OCT angiography. This article reviews the recent progress of OCT technology applied to organ microcirculatory study especially focusing on OCT angiography.

View full abstract