We investigated the developmental characteristics and sensor y profiles of children with Down syndrome. We requested parents of children who have been able to walk by performing "Baby Exercises for Children with Down Syndrome" at our clinic, to fill out the "Japanese version of sensory profile (SP)" and "Modified Checklist for Autism in Toddlers (M-CHAT)." We received responses from 17 families. In SP, the percentage of low registration was "probable difference" was significantly higher (p<0.001). In the examination of sensory processing items, 41% of the children were found to have problems with oral sensation (p=0.041). The results showed that children with high sensory quest started walking at a later age. Eight (47.1%) were positive for M-CHAT screening. There was no difference in SP values between those who were positive and those who were negative in M-CHAT. For advancing the rehabilitation of children with Down syndrome, it is necessary to consider measures that are commensurate with individual sensory characteristics.