YAKUGAKU ZASSHI
The Pharmaceutical Society of Japan, established in 1880, is one of Japan’s oldest and most distinguished academic societies. The Society currently has around 18,000 members. It publishes three monthly scientific journals. Chemical and Pharmaceutical Bulletin (Chem. Pharm. Bull.) began publication in 1953 as Pharmaceutical Bulletin. It covers chemistry fields in the pharmaceutical and health sciences. Biological and Pharmaceutical Bulletin (Biol. Pharm. Bull.) began publication in 1978 as the Journal of Pharmacobio-Dynamics. It covers various biological topics in the pharmaceutical and health sciences. A fourth Society journal, the Journal of Health Science, was merged with Biol. Pharm. Bull. in 2012. Yakugaku Zasshi (Japanese for “Pharmaceutical Science Journal”) has the longest history, with publication beginning in 1881. Yakugaku Zasshi is published mostly in Japanese, except for some articles related to clinical pharmacy and pharmaceutical education, which are published in English.
The main aim of the Society’s journals is to advance the pharmaceutical sciences with research reports, information exchange, and high-quality discussion. The average review time for articles submitted to the journals is around one month for first decision. The complete texts of all of the Society’s journals can be freely accessed through J-STAGE. The Society’s editorial committee hopes that the content of its journals will be useful to your research, and also invites you to submit your own work to the journals.

Chairman of Committee
Ken-ichi Hosoya
Graduate School of Medicine and Pharmaceutical Sciences, University of Toyama 
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Published by The Pharmaceutical Society of Japan  
16,854 registered articles
(updated on June 22, 2018)
Online ISSN : 1347-5231
Print ISSN : 0031-6903
0.324
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Featured article
Volume 138 (2018) Issue 6 Pages 829-836
Endogenous Serotonin and Milk Production Regulation in the Mammary Gland Read more
Editor’s picks

Intrinsic 5-HT synthesized within the mammary epithelium has an important physiological role in milk volume homeostasis. When the mammary gland becomes filled with milk, 5-HT provides a negative feedback signal that suppresses further milk synthesis in the mammary epithelium. Our research, using MCF-12A cells, shows that the expression of b-casein, a differentiation marker, is suppressed via 5-HT-mediated inhibition of STAT5. Additionally, our results show that reduced b-casein expression in the cells is associated with 5-HT7 receptor and PTP1B activation.

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