The rate of blood flow of full-thickness iliac bone grafts over a 2-month-interval was studied in 32 adult white rabbits, using the hydrogen washout technique.
Our results were as follows.
1. Two weeks after transplantation, blood flow was observed in each type of grafts, but its rate in autografts were significantly higher than that in allografts.
2. Blood flow of autografts proceeded rapidly for 4 weeks and peaked at 4 weeks, followed by a slow decline.
3. Blood flow of allografts did not show an initial rise and remained significantly lower than that of autografts for 4 weeks.
4. The hydrogen washout technique was found to be useful for long term and repetitive determinations of the rate of bone blood flow, such as this experiment in bone grafts.
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