幼児型ceroid lipofuscinosis 1症例の電気生理学的変化を検討した. 3歳時の脳波では棘波・高振幅徐波は後頭部優位で, その後高振幅徐波は次第に全汎化し, 棘波は多焦点性に出現した. 5歳時にmulti-modality evoked potentialsを施行した. 巨大視覚および体性感覚誘発電位・C-responseが導出され, 大脳皮質の易刺激性およびcortical reflex myoclonusが存在すると考えられた. 病気の進行とともに眼輪筋反射の潜時は延長し脳幹部三叉神経-顔面神を認めたが, 聴性脳幹反応は正常で脳幹部聴覚路機能は保たれていた. 種々の電気生理学的検査を併用することは病気の進行をみるうえで有用と考える.

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 1. Introduction
 The objective of simulation is to understand the content of a construction plan and to clarify the problems in the plan to be improved, by simulating the progress in accordance with a construction plan before the construction start. This paper proposes a modeling of simulating workers' movement at construction site, and suggest incorporating algorithmic planning methods into the simulation model. Then, using a case study, the author verifies the validity of these modeling methods.
 2. Workers' movement at a construction site
 The author describes the characteristics of moving-type work in a building construction, and points out that geometrical planning of a site is indispensable for grasping workers' movement and transportation of materials by workers.
 3. Modeling of workers' geometrical position
 In order to indicate geometrical position at a site as a model, quadtree-structured 'Cells' are used. Cells represent floors where workers are moving and materials are transported. Thus, the accurate position of workers at each time can be grasped by workers' movement among these Cells.
 4. Modeling of Rrepetitive work Process
 The author mentions that the interval of simulation of workers' movement and transportation of materials should be 1 to 3 seconds, and suggests that modeling of repetitive work process is necessary in order to model building construction at such a small interval. The author also presents the method of representing repetitive work process using a model, together with the method of autonomously selecting a repetitive work process while taking work progress into consideration.
 5. Modeling of Moving-type work
 Here presents a method of modeling moving-type work. In addition to a model using 'nodes' and 'arrows' in the past study, this method uses 'scripts' to describe detailed actions during work. Thus, it becomes possible to autonomously search the shortest path of workers' movement, and accurately simulate actions such as holding or releasing materials to be transported.
 6. Algorithmic planning
 Planning Items such as Workers' moving path, layout of materials at a yard, and sequence of installation of components are not clearly decided at the construction start time, therefore the system should make a plan autonomously and incorporate the content of these plans into a simulation model. The methods of algorithmic planning are defined for planning of workers' autonomous actions required in the case study in Chapter 7.
 7. Case study
 A building with many individual research rooms is used for this case study, which focuses on a process of installing partition panels. This process consists of the following three repetitive work process; (1) transporting panel tracks, (2) transporting and installing panels, and (3) transporting vacant tracks. The author develops a model that incorporates algorithmic planning into simulation, and makes a work scheduling chart as well as a manpower scheduling chart. Then, the author verifies that simulation enables workers to proceed with actions by autonomously to be required to complete works.
 8. Conclusion
 This paper verified that the progresses of workers' movement and transporting works are simulated accurately by the proposed simulation models

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