It was studied endoscopically that effects of submucosal blood flow in the canine stomach of three mongrel dogs on Nd-YAG laser radiation.
The Nd-YAG laser (Medilas; M. B. B.) was fired endoscopically at 30w, 50w & 80w by a jet of CO
2 coaxially optical fiber through the forceps channel with exposure durations of 4.0 seconds. The top of the wave guide was placed at about 1.0 to 2.0cm from the mucosal surface. At the same time, gastric submucosal blood flow was measured using hydrogen electrode through the gastric serosa and muscular layer at the lesser and greater curvature of the gastric body. Histological findings were examined with HE stain, Azan stain and E. V. G. stain.
The quartz fiber with CO
2 gas-jet was more flexible and pass through more easily to the biopsy channel of upper G. I. endoscope (GF-B
3, GIF-D
2; Olympus) than that without coaxial CO
2. In case of decreased submucosal blood flow, histological damages were noted deep through the muscular layer in the canine stomach. On the contrary, increase of submucosal blood flow resulted shallow histological change limited submucosal layer with the same exposure condition of Nd-YAG laser. It was suggested that the endoscopical application of Nd-YAG laser radiation was influenced with organic blood flow in the gastrointestinal tract.
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