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  • Yasunori SAITO, Tomoyuki MARUYAMA, Hideaki YAMAKI, Fumitoshi KOBAYASHI, Takuya
    D
    . KAWAHARA, Akio NOMURA, Mitsuyoshi TANAKA
    Optical Review
    1999年 6 巻 5 号 459-463
    発行日: 1999/10/01
    公開日: 2000/03/28
    ジャーナル フリー
    Static characteristics of two different structured InAlGaAs/InAlAs superlattice avalanche photodiodes (SLAPDs) cooled by liquid nitrogen were evaluated at a wavelength of
    1
    .5 μm. The dark current of the SLAPD having a thick superlattice layer of 0.504 μm was 5×10-13 A. This was successively reduced by four orders of magnitude compared to that of the thin layer SLAPD of 0.231 μm at a breakdown voltage of around 20 V. The thickened layer was effective in suppressing tunneling dark current. An output current of
    1
    .7×10-12 A at a bias voltage of 15 V was measured for an optical input with a wavelength of
    1
    .5 μm and a signal power of
    1
    ×10-12 W. This showed a sharp distinction from the dark current.
  • 山口 昭彦
    日本中東学会年報
    1994年 9 巻 37-65
    発行日: 1994/03/31
    公開日: 2018/03/30
    ジャーナル フリー
    L'entree en Iran des armees britannique et sovietique s'est produite en aout 1941. Elle ebranla du coup le regime de la dynastie pahlavi qui etait au pouvoir depuis 16 ans, et mena le pays vers l'instabilite politique et le chaos social. La defaite de l'arme gouvernementale, qui etait le pivot du regime de Reza Shah, reduisit considerablement le controle du gouvernement central dans le pays. Cette situation politico-sociale confuse permit le developpement de differents mouvements politiques en Iran. C'est ainsi que le 16 aout 1942 le parti clandestin Komeley Jiyanewey Kurdistan (J-K) est ne a Mehabad, une ville au nord-ouest de l' Iran. Des sa formation, ce parti a su etendre sa sphere
    d'activite
    et, en une courte periode de temps, a fini par mettre sous son influence la ville et ses alentours. A la fin de la Seconde Guerre mondiale, en ete 1945, le J-K etait devenu une organisation representant le mouvement nationaliste kurde en Iran. C'est a ce moment-la qu'un autre parti politique, le Hizbi Dimokratiki Kurdistan (HDK), fonde par Qazi Mihemed a Mehabad aussi, devait remplacer le J-K. Des le
    22
    janvier 1946, le HDK proclama l'instauration de la≪Republique de Kurdistan≫. Cependant, les troupes sovietiques qui avaient pris sous leur protection la Republique evacuerent les terres iraniennes, en mai 1946. Six mois plus tard, sous la pression militaire du gouvernement central iranien, la republique s'ecroula. Deux theories tentent
    d'expliquer
    le passage du J-K au HDK. William Eagleton Jr., par exemple, affirme dans The Kurdish Republic of 1946 que le HDK a ete cree sur le conseil des autorites sovietiques. L'ex-secretaire general du Parti Democratique du Kurdistan
    d'Iran
    , 'Ebd el-Rehman Qasimlu maintient par contre que Qazi Mihemed a etabli le nouveau parti de sa propre initiative, eu regard a la situation politique de cette epoque-la. Il considere que la passage du J-K au HDK comme etant l'evolution
    d'un
    parti nationaliste clandestin en un parti democratique. En analysant ces deux theories et en se basant sur les autobiographies des personages qui se sont engages dans cet evenement, cette etude tentera
    d'examiner
    le principe directeur et les activites du J-K et de mieux comprendre les raisons pour lesquelles le J-K devait etre remplace par le HDK. La conclusion generale portera sur les differents objectifs politiques du J-K et du HDK. Le J-K visait l'elevation du niveau culturel du peuple tout en luttant contre le tribalisme, qui etait, selon lui, le probleme majeur de≪la nation kurde≫, et cela en ecartant toute idee de revolte militaire. Le J-K a aussi exclu de son cadre les elites sociales telles que les leaders des tribus et dirigeants religieux de peur qu'ils n'excercent une influence sur les membres du parti. L'automne de 1944 fut le debut
    d'une
    nouvelle ere pour le mouvement kurde. Alors que l'espoir de l'autodetermination augmentait parmi le peuple a mesure que s'approchait la fin de la guerre, la necessite de la force militaire a commence a se faire sentir dans le J-K. C'est pour cela que s'est produite au sein du parti une tendance a compter sur l'aide militaire des sovietiques et a recourir au leadership de Qazi Mihemed, qui avait une certaine influence meme sur les leaders tribaux. Mais cette tendance etait essentiellement incompatible avec la ligne fondamentale du J-K et, graduellement, a prive ce parti de sa raison
    d'etre
    . Ainsi, le HDK se substitua au J-K en tant que≪parti democratique≫visant a rallier
    d'abord
    les elites sociales sous sa banniere, en s'appuyant sur l'autorite personnelle de Qazi Mihemed.
  • 西日本皮膚科
    2019年 81 巻 3 号 Index3_1-Index3_2
    発行日: 2019/06/01
    公開日: 2019/08/06
    ジャーナル 認証あり
  • Tukasa KUROSAWA, Haruyuki KANAYA
    Neurologia medico-chirurgica
    1963年 5 巻 110
    発行日: 1963年
    公開日: 2007/05/25
    ジャーナル フリー
  • 西村 正巳
    日本機械学会誌
    1961年 64 巻 504 号 193-
    発行日: 1961/01/05
    公開日: 2017/06/21
    解説誌・一般情報誌 フリー
  • H. K. Mahanty
    CYTOLOGIA
    1970年 35 巻 1 号 13-49
    発行日: 1970/03/25
    公開日: 2009/03/19
    ジャーナル フリー
    1
    . The chromosome numbers of 64 species have been studied on which 56 are investigated for the first time.
    2. Morphological, anatomical and cytological findings on the Musaceae in the broad sense are considered from a phylogenetical standpoint and three distinct groups:
    a) Musa-Ensete, b) Ravenala-Strelitzia-Phenakospermum and c) Holiconia are recognised as suggested by some authors. For these groups sub-familial status is proposed.
    3
    . Lowiaceae have been studied for the first time cytologically and their chromosome morphology, distinct from that of any other group of Zingiberales, confirms their claim to familial status.
    4. Consideration of the conflicting theories proposed to account for the higher chromosome number in genera like Globba, Alpinia, and Phaemeria, etc. leads to rejection of Chakravorti's hypothesis of wholesale fragmentation of chromosomes and the acceptance of the opposed view of Raghavan and Venkatasubban and others.
    5. Holttum's transference of the genus Zingiber to the tribe Hedychieae has been given cytological support on the following points:
    a) the basic number in the genus Zingiber correlates with that of Kaempferia.
    b) the new tribe Alpinieae (which is infact Zingibereae without Zingiber) have consistently 48 chromosomes in their somatic complements.
    6. It is suggested that the African representatives of Kaempferia should be given the status of genus; Cienkowskya on the following points:
    a) the difference in floral morphology
    b) geographical separateness and
    c) the difference in the number and morphology of the chromosomes. By comparing the present and past findings, various lines of evolution of the chromosome complements within each group are discussed.
    7. The basic number 11 is considered to be probably the original one for the Zingiberales as a whole, being present in Ravenala which is the most primitive member in the order. From this secondary basic numbers have arisen through evolution.
  • Mitsuhiko KATAOKA
    地域学研究
    2010年 40 巻 4 号 1061-1072
    発行日: 2010年
    公開日: 2011/05/20
    ジャーナル フリー
    Using the Theil population-weighted method for per capita GDP and the variance in a shift-share analysis on labor productivity, we conduct a comprehensive interregional income inequality decomposition analysis on Indonesia before and after the 1998 economic crisis.
    Interregional income inequality is largely determined by the interregional inequality in the productivity differential component due to the region's specific sector-by-sector productivity differentials—the result of investments accumulated in technology, public infrastructure and human capital. Although the interregional inequality in the productivity differentials show a declining trend throughout the period under observation, they should have decreased further, considering the active implementation of policies aimed at balanced regional development. However, the results are still far below the target levels because of the effects of economic agglomeration. An examination of non-productivity factors shows that the interregional inequality in the employment rate has become the dominant factor after the crisis, whereas the active population rate was dominant before. The widening of the interregional employment gap is a new concern for Indonesia. The relative decrease in urban employment rates in 2003-2006 and the predominance of inequality in higher educational attainments within the urban sector reported by Akita and Miyata[5]suggest a growing deterioration in the labor market efficiency in urban regions.

    JEL Classification:
    D
    63, O40, R11, R58
  • *PRADEEP KUMAR SHRESTHA, YORDPHOL TANABORIBOON, SHINYA HANAOKA
    Proceedings of the Eastern Asia Society for Transportation Studies
    2007年 2007 巻
    発行日: 2007年
    公開日: 2008/04/04
    会議録・要旨集 フリー
    The travel behavior is a result of complex decision making process affected by individual's socioeconomic, mode and trip characteristic as well as unobserved variables. The focus of this research was to identify the unobserved factors influencing travel behavior. Six latent variables named as travel factors were identified through factor analysis. Structural equation modeling (SEM) was used to identify casual relationship between observed variables and travel factors. It was noted that SEM cannot predict the travel demand but it has ability to express relationships between unobserved and observed variables. Then, travel factors were employed in discrete choice model to consider individual preferences on unobserved variables. It was found that the model with travel factors perform superior than model without travel factors. Conclusively, the further application of these factors in its different forms can effectively measure their effect in the travel demand model.
  • Philippe Biane
    Publications of the Research Institute for Mathematical Sciences
    1995年 31 巻 1 号 63-79
    発行日: 1995年
    公開日: 2009/04/24
    ジャーナル フリー
  • 土岐 實光
    日本機械学会誌
    1949年 52 巻 371 号 422-423
    発行日: 1949/11/25
    公開日: 2017/06/21
    解説誌・一般情報誌 フリー
  • 大東 弘明, 石川 治, 中森 正二, 佐々木 洋, 今岡 真義, 岩永 剛
    日本消化器外科学会雑誌
    1986年 19 巻 7 号 1629-1638
    発行日: 1986年
    公開日: 2011/03/02
    ジャーナル フリー
    切除不能膵癌10例に対し, 開腹下に超選択的に脾動脈あるいは胃十二指腸動脈に挿管し, 血管作動性薬剤であるAngiotensin-IIを併用した抗癌剤注入による動注化学療法を行った.また, methotrexate使用例には十二指腸などに対するrescueの投与時に, Prostaglandin
    E1
    を併用した.この際の, 膵における血流動態を水素ガスクリアランス法やradioisotope (
    81mKr
    ) を用いて測定した.膵癌の組織血流は
    22
    .
    9
    ±17.4mlで非癌部膵の
    1
    /
    3
    と低値であったが, Angiotensin-IIにより (腫瘍/非腫瘍部膵) の比 (T/C) は0.48から
    1
    .2と増加し, 腫瘍部全体の血流も, 2.
    1
    倍に増加し, 腫瘍への薬剤の選択性, 到達性が高められた.逆に, Prostaglandin
    E1
    併用では, T/Cが0.33から0.21へと減少し, 腫瘍への選択性が低下した.
  • 日本水産学会誌
    2015年 81 巻 4 号 769-771
    発行日: 2015年
    公開日: 2015/08/13
    ジャーナル フリー
  • 馬場 輝郎
    照明学会雑誌
    1968年 52 巻 3 号 107-111
    発行日: 1968/03/25
    公開日: 2011/07/19
    ジャーナル フリー
  • 布施川 雄一, 多田 博己, 小熊 利明, 椎名 豊, 玉地 寛光, 半田 俊之介
    動脈硬化
    1996年 23 巻 9 号 545-551
    発行日: 1996/04/10
    公開日: 2011/09/21
    ジャーナル フリー
    The association between apolipoprotein
    E
    (Apo-
    E
    ) polymorphism and the response of plasma cholesterol to dietary therapy (cholesterol intake of less than 300mg/day) was investigated for about 8 weeks in 208 nonfamilial hypercholesterolemia patients (
    E
    3
    /
    3
    161,
    E
    4/
    3
    47). The baseline lipoprotein concentration and the intake of energy and lipids were not significantly different between subjects with
    E
    3
    /
    3
    and those with
    E
    4/
    3
    phenotypes. After the dietary therapy plasma total cholesterol and low density lipoprotein cholesterol were significantly decreased in both phenotype groups (p<0.05). The patients with
    E
    4/
    3
    had significantly smaller reductions of LDL-C than the patients with
    E
    3
    /
    3
    . The changes of LDL-C showed a significant difference between the patients with
    E
    3
    /
    3
    and
    E
    4/
    3
    by the Kruskal Wallis test (p=0.041). The presence of
    E
    4/
    3
    predicted the degree of cholesterol reduction following dietary therapy.
  • 大沢 水澄
    日本機械学会誌
    1967年 70 巻 578 号 449-450
    発行日: 1967/03/05
    公開日: 2017/06/21
    解説誌・一般情報誌 フリー
  • 等電点ゲル電気泳動法を用いたアポ蛋白Eの Isoform の検討
    上田 幸生, 吉村 陽, 若杉 隆伸, 渡辺 彰, 多々見 良三, 上田 良成, 亀谷 富夫, 羽場 利博, 小泉 順二, 宮元 進, 馬淵 宏, 竹田 亮祐
    動脈硬化
    1981年 8 巻 4 号 745-751
    発行日: 1981/01/01
    公開日: 2011/09/21
    ジャーナル フリー
    According to Utermann et al, Apo
    E
    is usually separated into three major isoforms, ie
    E
    1
    ,
    E
    2,
    E
    3
    , and he reported three phenotypes of Apo
    E
    , Apo
    E
    -N, Apo
    E
    -ND, Apo
    E
    -
    D
    , according to the Apo
    E
    2/
    E
    3
    ratios.
    In this study we examined Apo
    E
    polymorphism by isoelectric focusing and ultracentrifugal lipoprotein analysis in 124 Japanese subjects including 5 patients with primary type III hyperlipoproteinemia.
    Following results were obtained.
    1
    ) The Apo
    E
    protein focused into four main bands, Apo
    E
    1
    ′,
    E
    1
    ,
    E
    2,
    E
    3
    (normal pattern) and fifth band (Apo
    E
    4), (variant pattern).
    2) In primary type III hyperlipoproteinemia, Apo
    E
    3
    was deficient, wherease Apo
    E
    2 and Apo
    E
    1
    increased.
    3
    ) We examined distribution of Apo
    E
    patterns according to Apo
    E
    3
    /
    E
    2 ratios in 124 subjects. The distribution of the Apo
    E
    3
    /
    E
    2 ratios showed a trimodality. All the patients with primary type III hyperlipoproteinemia were in the lowest mode (
    E
    3
    /
    E
    2 below 0.
    3
    ) which represents Apo
    E
    -
    D
    . In the remainders, 34 subjects were in the middle mode (
    E
    3
    /
    E
    2, between 0.6-
    1
    .4) which represents Apo
    E
    -ND. and 85 subjects were in the highest mode (
    E
    3
    /
    E
    2 above
    1
    .5) which represents Apo
    E
    -N.
    These cutoff points correspond to those which Utermann had reported in the German populations. Thus, there were no differences in Apo
    E
    phenotypes between Japanese and German populations.
    4) In
    3
    patients out of 5 patients with primary type III hyperlipoproteinemia, we measured postheparin lipolytic activity. Two cases (H. N., M. K.) showed a decreased hepatic lipase activity (H-TGL) and a normal lipoprotein lipase activity (LPL).
    But one case (S. I.) showed a normal H-TGL and LPL.
    5) VLDL-TC/VLDL-TG and VLDL-TC/whole serum TG ratios were higher in Apo
    E
    -ND than in Apo
    E
    -N, and higher in Apo
    E
    -
    D
    than in Apo
    E
    -ND.
    These results suggests that Apo
    E
    3
    deficiency had a effect which increases lipoprotein remnants.
  • HYOZO TANIYAMA, YOSUKE SAWADA
    The Journal of Antibiotics
    1971年 24 巻 10 号 708-709
    発行日: 1971/10/25
    公開日: 2006/04/12
    ジャーナル フリー
  • R. I.・Ittrich-Fluorometry
    田中 啓幹
    日本泌尿器科學會雑誌
    1969年 60 巻 12 号 1125-1142
    発行日: 1969年
    公開日: 2010/07/23
    ジャーナル フリー
    Urinary estrogens have been assayed chiefly with the Kober hydroquinone colorimetry or sulfuric acid fluorimetry. However, it is difficult to determine accurately small amounts of estrogens such as in urines from males, oophorectomized women or menopausal women. In this study, male urinary estrogens were determined by a modification of the method reported by Kambegawa and some experimental studies were made on male urines. 200ml aliquot of 24-hour urine is hydrolyzed by the
    3
    -step hydrolysis, added with estrone-6, 73H, 17β-estradiol-6, 73H and estriol-6, 73H, and extracted with ether, followed by alkaline washes, methylation by a supersonic wave mixer, thin layer and column chromatography, liquid scintillation spectrometry and the Ittrich fluorometry. Results of experimental studies and estimation of urinary estrogens in males are as follows:
    1
    ) After the
    3
    -step hydrolysis, 54.5% of the urinary estrogens were collected as the glucuronide, 30% in the solvolyzed fraction and 15.5% as the hot acid hydrolyzate. 2) The methylation of estrogens was achieved 10-20% better by the use of the supersonic wave mixer than by a magnetic stirrer.
    3
    ) Calculating efficiency of the Packard Tri-carb liquid scintillation spectrometer was tested in varieties of the estrogen concentrations using the dilution and the external standardization methods. There was noted no influence of the estrogen concentrations on the counting efficiency in the determination ranges. 4) In the range of 2×10-
    3
    -
    1.0μg
    , a linear relationship on the standard curve was obtained applying the Allen's correction, when fluorometry was conditioned with the excitation light wave length of 510mμ and the fluorescence wave lengths of 530, 550 and 570mμ for each of the three estrogen-methyl ethers. 5) Urinary estrogens were determined in 15 normal males. In 5 subjects (2-13 years old) the values were:
    E1
    :
    1
    .06±
    1
    .09;
    E2
    : 0.64±0.54;
    E3
    : 0.76±0.68 and the total
    E
    : 2.46±
    1.99μg
    /24hr. In 5 men (
    22
    -38 years old),
    E1
    : 5.02±
    1
    .57;
    E2
    : 2.58±0.21;
    E3
    : 4.11±
    1
    .
    82
    and the total
    E
    : 11.72±2.97μg/24hr. In 5 men (46-72 years old),
    E1
    :
    3
    .
    81
    ±0.31;
    E1
    :
    1
    .71±0.48;
    E3
    :
    3
    .51±0.
    94
    and the total
    E
    :
    9
    .03±
    1.33μg
    /24hr. 6) Urinary estrogens were also determined in patients with a variety of clinical syndromes.
  • 斉 洋之, 高津戸 秀, 池川 信夫, 田中 洋子, スミス コニー, デルカ F.ヘクター
    Chemical and Pharmaceutical Bulletin
    1984年 32 巻 10 号 3866-3872
    発行日: 1984/10/25
    公開日: 2008/03/31
    ジャーナル フリー
    Chemical synthesis of (
    22
    E
    , 24R)- and (
    22
    E
    , 24S)-
    1
    , 24-dihydroxy-
    Δ22
    -vitamin
    D3
    has been achieved starting with the commercially available dinorcholenic acid acetate. Synthesis involved introduction of the
    1
    -hydroxy group by a reduction of the
    1
    , 2-epoxide generated by epoxidation of the
    1
    , 4, 6-trien-
    3
    -one. The side chain on the steroid was then constructed by means of a Wittig reaction followed by introduction of the Δ7 bond by standard methods and its protection with
    1
    -phenyl-
    1
    , 2, 4-triazoline-
    3
    , 5-dione. Subsequent reduction of the hydroxy groups in the steroid side chain followed by reduction of the Diels-Alder addition products yielded the both 24-isomers. The 5, 7-dienes were irradiated and the corresponding vitamin
    D
    compounds isolated. Nuclear magnetic resonance was used to identify individual isomers. The (
    22
    E
    , 24S)-
    1
    , 24-hydroxyvitamin
    D3
    compound bound equally well to the chick intestinal cytosol receptor as
    1
    , 25-dihydroxyvitamin
    D3
    , while the 24R-isomer was approximately ten times less active. In vivo, both isomers were less active than
    1
    , 25-dihydroxyvitamin
    D3
    ; however, the 24S-isomer was considerably more active than the 24R-isomer approaching the activity of
    1
    , 25-dihydroxyvitamin
    D3
    .
  • Keishi Hata, Fuyuki Sugawara, Naganori Ohisa, Saori Takahashi, Kazuyuki Hori
    Biological and Pharmaceutical Bulletin
    2002年 25 巻 8 号 1040-1044
    発行日: 2002年
    公開日: 2002/08/01
    ジャーナル フリー
    We screened the differentiation-inducing activities of 39 mushroom extracts from Akita prefecture, Japan, on the mouse osteoblastic cell line, MC
    3
    T
    3
    -
    E
    1
    . Sixteen phosphate buffered saline (PBS), 8 boiled PBS, 14 ethanol and 12 methanol extracts induced alkaline phosphatase (ALP) activities, an indicator of MC
    3
    T
    3
    -
    E
    1
    cell differentiation. The enzyme activities were markedly induced by extracts of Tricholoma auratum, and we isolated the active compound from methanol extracts of this mushroom. Physical data for the isolated active compound were identical to those for (
    22E
    ,24R)-ergosta-7,
    22
    -diene-
    ,5α,6β-triol (
    1
    ).
    1
    induced ALP activities of MC
    3
    T
    3
    -
    E
    1
    cells and promoted cell proliferation. To investigate the relationships between the chemical structure and differentiation-inducing activity of the compound, ALP-inducing activities of MC
    3
    T
    3
    -
    E
    1
    cells by
    1
    , ergosterol (2), ergocalciferol (
    3
    ), cholesta-
    ,5α,6β-triol (4), 7-dehydrocholesterol (5) and cholecalciferol (6) were tested. The enzyme activities of MC
    3
    T
    3
    -
    E
    1
    cells were increased
    3
    .0-fold by 10 μM
    1
    and 2.4-fold by 10 μM 4. However, 2,
    3
    , 5 and 6 did not induce MC
    3
    T
    3
    -
    E
    1
    cell ALP activity at 0.
    1
    —10 μM. These results suggested that the OH groups at C-5 and/or C-6 of
    1
    and 4 played an important role in their differentiation-inducing activities on MC
    3
    T
    3
    -
    E
    1
    cells. Furthermore,
    1
    suppressed induction of MC
    3
    T
    3
    -
    E
    1
    cell apoptosis by serum starvation.
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