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  • George W. Lee
    燃料協会誌
    1973年 52 巻 3 号 171-177
    発行日: 1973/03/20
    公開日: 2010/06/28
    ジャーナル フリー
  • Grover Loening
    日本航空学会誌
    1963年 11 巻 119 号 373-380
    発行日: 1963年
    公開日: 2009/05/25
    ジャーナル フリー
  • 小田切 孝人, 田代 眞人
    ウイルス
    2013年 63 巻 2 号 233-240
    発行日: 2013/12/25
    公開日: 2014/10/31
    ジャーナル フリー
  • A.M. BRITTO,
    C
    . SAVVIDOU, M.J. GUNN, J.R. BOOKER
    土質工学会論文報告集
    1992年 32 巻 1 号 13-25
    発行日: 1992/03/15
    公開日: 2008/02/29
    ジャーナル フリー
    One method currently being considered for the disposal of high level radio-active waste is burial in the seabed. When a hot object is buried in soil, the temperature of the soil adjacent to the object is raised and there is transient heat flow away from the object. The rise in the temperature of the soil causes excess pore pressures to be generated and transient pore water diffusion also takes place. A finite element formulation of the coupled heat flow and consolidation problem is presented. The computer implementation of this formulation is found to compare favourably with analytical solutions based on the same physical principles.
  • T BAKER,
    C
    . RANGACHARYULU
    日本物理学会講演概要集
    1999年 54.2.1 巻 23pSM-6
    発行日: 1999/09/13
    公開日: 2018/03/04
    会議録・要旨集 フリー
  • Cbesseredes HORTS
    Journal of Human Ergology
    1982年 11 巻 Supplement 号 429-440
    発行日: 1982/12/15
    公開日: 2011/02/23
    ジャーナル フリー
  • I.
    F
    . Davies
    Journal of Light & Visual Environment
    1984年 8 巻 1 号 1_9-1_20
    発行日: 1984年
    公開日: 2011/05/20
    ジャーナル フリー
  • Joey
    B
    . Tanney, Leonard J. Hutchison
    Mycoscience
    2012年 53 巻 1 号 31-35
    発行日: 2012年
    公開日: 2023/03/31
    ジャーナル オープンアクセス

    The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On

    2
    % modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

  • Zhe Fang, Su Yang Jeong, Hyun Ah Jung, Jae Sue Choi, Byung Sun Min, Mi Hee Woo
    Chemical and Pharmaceutical Bulletin
    2010年 58 巻 9 号 1236-1239
    発行日: 2010/09/01
    公開日: 2010/09/01
    ジャーナル フリー
    Activity-directed isolation of the ethyl acetate, methylene chloride and n-hexane fractions of Gloiopeltis furcata resulted in the isolation of 18 compounds. Their structures were elucidated as
    2
    -(3-hydroxy-
    5
    -oxotetrahydrofuran-3-yl)acetic acid (1), glutaric acid (
    2
    ), succinic acid (3), nicotinic acid (4), (
    E
    )-4-hydroxyhex-
    2
    -enoic acid (
    5
    ), cholesterol (6),
    7
    -hydroxycholesterol (
    7
    ), uridine (8), glycerol (
    9
    ),
    5
    -(hydroxymethyl)-
    2
    -methoxybenzene-1,3-diol (10), (
    5E
    ,
    7E
    )-
    9
    -oxodeca-
    5
    ,
    7
    -dienoic acid (11), (Z)-3-ethylidene-4-methylpyrrolidine-
    2
    ,
    5
    -dione (12), dehydrovomifoliol (13), loliolide (14), cholesteryl stearate (15), palmitic acid (16), cis-
    5
    ,8,11,14,17-eicosapentaenoic acid (17) and α-linolenic acid (18) on the basis of spectroscopic and chemical evidences. Their anticholinesterase and antioxidant activities were evaluated via inhibitory activities on acetylcholinesterase (AChE) and butyrylcholinesterase (BChE) as well as scavenging activities on 1,1-diphenyl-
    2
    -picrylhydrazyl (DPPH) radical and peroxynitrite (ONOO). All isolated compounds (118) exhibited moderate AChE inhibitory activities with IC50 values ranging from 1.14—12.50 μg/ml, whereas 1,
    7
    ,
    9
    , 17, and 18 showed mild BChE inhibitory activities with IC50 values ranging from
    5
    .57—15.89 μg/ml. Although most of the compounds isolated were lacking the scavenging activity on DPPH radical and ONOO,
    5
    and 10 showed good DPPH radical scavenging activity, and
    5
    , 10, and 16 showed potent ONOO scavenging activity.
  • 長谷川 親太郎
    The Keio Journal of Medicine
    1992年 41 巻 3 号 146-153
    発行日: 1992年
    公開日: 2009/03/27
    ジャーナル フリー
    Tumor-infiltrating lymphocytes (TIL) were tested for cytotoxicity against autologous tumor cells in a study utilizing a chemically induced cancer ofthe bladder (transitional cell carcinoma),
    BC
    -47, in inbred ACI/N rats. From tumors grown after subcutaneous implantation of
    BC
    -47 in the rats TIL were separated by density gradient centrifugation and incubated in plastic dishes for separation of non-adherent from adherent cells. The non-adherent cells were further fractionated into T and
    B
    cells by the panning method using anti-rat
    F
    (ab')
    2
    antibody. The cell fractions were each added to
    BC
    -47 in culture to be assessed for antitumor effect by the crystal violet dye exclusion method and 3H-thymidine incorporation inhibition assay. Peripheral blood mononuclear cells (PBMC) were also tested as described above. TIL expressed significantly higher cytotoxicity against
    BC
    -47 with the mean % cytotoxicity of 56.6±
    5
    .6% and 87.
    5
    ±
    7
    .1% at
    E
    /T ratios of 10:1 and 20:1, respectively, as compared to PBMC(
    9
    .
    9
    ±
    5
    .
    0
    % at
    E
    /T 10:1) (P<
    0
    .001). The adherent cells,
    B
    and T cell fractions showed respective % cytotoxicity of 92.4±
    2
    .8%, 57.
    9
    ±10.6% and
    9
    .
    9
    ±
    7
    .8% at an
    E
    /T ratio of 10:1. TIL pretreated with IFN or rIL-
    2
    for 24or 48 hours did not exhibit any noticeably enhanced antitumor activity at an
    E
    /T ratio of
    5
    :1. Prevention of direct contact of
    BC
    -47 cells and TIL by an interposed Millipore membrane (
    0.45μm
    ) resulted in an unequivocal reduction of antitumor effect. This finding clearly indicates that the direct contact with
    BC
    -47cells and TIL is necessary for TIL to manifest their cytotoxicity against the autologous tumor cells, suggesting that TIL exhibit autologous tumor killing activity through cell-mediated cytotoxicity.
  • Özkan ASLANTAŞ, Ebru Şebnem YILMAZ
    Journal of Veterinary Medical Science
    2017年 79 巻 6 号 1024-1030
    発行日: 2017年
    公開日: 2017/06/16
    [早期公開] 公開日: 2017/04/27
    ジャーナル フリー

    This study aimed to determine the prevalence of fecal carriage of extended spectrum β-lactamase (ESBL) and/or plasmidic AmpC β-lactamase (pAmpC) producing Escherichia coli among dogs (n=428) in Turkey. Polymerase chain reaction (PCR) and sequencing were used to characterize genes encoding β-lactamase and plasmid mediated quinolone resistance (PMQR). Antimicrobial susceptibility testing and PCRs for virulence genes and phylogenetic groups were also performed. Cefotaxime resistant

    E
    . coli isolates were detected in
    95
    (
    22
    .
    2
    %) of the swab samples. Sequencing analysis results showed occurrence of various β-lactamase genes: blaCTX-M-15 (62), blaTEM-
    1b
    (42), blaCMY-
    2
    (
    22
    ), blaCTX-M-3 (16), blaCTX-M-1 (15), blaOXA-1 (
    9
    ) and blaSHV-12 (3) alone or in combination. The most frequently encountered phylogenetic group was group A1 (35.8%), followed by group
    D2
    (
    22
    .1%),
    B
    1 (15.8%), D1 (
    9
    .
    5
    %),
    A0
    (
    7
    .4%),
    B22
    (
    5
    .3%) and
    B23
    (4.
    2
    %), respectively. PMQR genes, aac(6’)-Ib-cr, qnrS1 and qnrB10 were detected in 25.3, 10.
    5
    and 1.1% of the isolates, respectively. While all isolates were susceptible to imipenem and amikacin, resistance rates to non-β-lactam antibiotics ranged from 20.
    0
    % for tobramycin to 56.8% for tetracycline. The virulence genes were only detected in 34 (36.
    2
    %) of the isolates and this isolates carried single or various combination of virulence genes of iucD, papC, papE,
    f17a
    -A and eaeA. Four isolates were identified as human virulent pandemic CTX-M-15 producing
    E
    . coli
    clone O25
    b
    :ST131/
    B
    2
    . To the best of our knowledge, this is the first study to show fecal carriage of ESBL/pAmpC type β-lactamase producing
    E
    . coli
    isolates among dogs in Turkey.

  • Yasuhiro SUGIMOTO, Kazuma SAKATOH
    IEICE Transactions on Electronics
    2013年 E96.C 巻 6 号 867-874
    発行日: 2013/06/01
    公開日: 2013/06/01
    ジャーナル 認証あり
    Circuit techniques to enhance the linearity of input-voltage-to-current (V/I) conversion and to increase the output impedance of a current source by compensating for the low intrinsic gain of a transistor were introduced to realize a high-frequency operational transconductance amplifier (OTA) for a low supply voltage using sub-100-nm CMOS processes. Applying these techniques, a MOS
    7
    th-order Gm-
    C
    linear-phase low-pass filter (LPF) was realized using a 65nm CMOS process. A simplified biquad LPF that can serve as a component of a
    7
    th-order LPF was newly developed by replacing OTAs with resistors. As a result, the -3dB frequency bandwidth, group delay ripple, 3rd-order distortion, and 3rd-order input intercept point (IIP3) were 200MHz,
    2
    .
    2
    %, ≤ -55dB with a 100MHz input, and +10.3dBm, respectively, all with a ±
    0
    .1Vp-p input signal at each input terminal in the pseudodifferential configuration. The LPF including an output buffer dissipated 60mW in the case of a 1.
    2
    V supply. Wide spurious-free dynamic range (SFDR) characteristics were confirmed up to high frequencies.
  • 和田 昭盛, 平石 佐栄子, 伊藤 允好
    Chemical and Pharmaceutical Bulletin
    1994年 42 巻 3 号 757-759
    発行日: 1994/03/15
    公開日: 2008/03/31
    ジャーナル フリー
    Stereoselective synthesis of
    7
    E
    ,
    9
    E
    - and
    7
    E
    ,
    9
    Z-β-ionylideneacetaldehydes was accomplished from the β-ionone tricarbonyl iron complex, and the latter was converted to
    9
    Z-retinoic acid.
  • 佐藤 敬之輔
    デザイン学研究
    1970年 1970 巻 11 号 45-55
    発行日: 1970/03/30
    公開日: 2017/07/25
    ジャーナル フリー
    [1] The purpose of this reserch is to make clear what type of design can give good effects to win the high readership score. At the begining I had to know what factors decide the readership score, and how to change the quality of the desing into numerical value. I have used the method of multi-dimentional analysis with the help of a computer, and got the estimation formula, with
    7
    kinds of factors, as follows ; A^^〜=
    B
    +
    C
    +D+K+aE+bF+cG. A^^〜=estimated values of the readership score. 1)
    B
    ,
    C
    , D, K : these four factors are given as category values (so we call them); each factor is classified into several categories.
    B
    =week day, classified into
    7
    categories.
    C
    =pages of a newspaper, which are characterized by the kinds of articles, news, and the other reading matters, classified into
    22
    categories. D=kinds of goods and trades of the advertizement, classified into 14 catedories. K=constants, given to each 13 surveys.
    2
    )
    E
    ,
    F
    , G : these factors are given as numerical values. G=area of advertizement, measured by the unit of column in the whole page length, being classified into 6 kinds of area (
    2
    .
    5
    , 3.
    5
    ,
    5
    ,
    7
    , 10, 15) and 15 column means a whole page, about
    2
    ,000cm^
    2
    .
    E
    ,
    F
    are the marks obtained in the design of advertizements.
    E
    =sum of the marks obtained in each design element on the advertizement.
    F
    =the marks obtained on the whole effect of the design. 3) a,
    b
    ,
    c
    : coefficients Using the above formula with the category values and the coefficients, we can obtain the naked design effect from the actual value A of readership score: aE+bF=A-(
    B
    +
    C
    +D+K+cG). In this research, I used 1,829 data of readership score from 1960 to 1968, being obtained by 13 survevs, spring and autumn twice a year. The sample of size each survey was 3,541,
    2
    ,251, or 200 in the other 11 surveys. Multiple correlation coefficient between the estimated value A^^〜 and the actual value A is
    0
    .951. The table
    2
    ^* shows the contribution indexes of each factor by 3 kinds of expression-(1) Range : the absolute difference between the maximum and the minimum category values, (
    2
    ) Standard deviations of the category values, (3) Partial correlation coefficient : the relationship between the actual values A and each factors. *see the table
    2
    in the thesis in Japanese. [
    2
    ] The important point was in the determination of the values of
    E
    ,
    F
    .
    E
    is the sum of the marks obtained in each design element, classified into four kinds :
    E
    =
    E
    _1+
    E
    _
    2
    +
    E
    _3+
    E
    _4. design elements [table]
    E
    _1,
    E
    _
    2
    ,
    E
    _3,
    E
    _4, these values have the
    5
    grades, as
    0
    , 1,
    2
    , 3, 4 and
    0
    is given to the design that has no attractive effect or no applicable element. And
    E
    obtain the marks of
    0
    to
    9
    grades as the sum of them. The values of
    F
    have also
    5
    grades,
    0
    to 4. The principles to determine the values of
    E
    ,
    F
    are as follows : a) The marks obtained of
    E
    ,
    F
    must be the relative values among the each survey, and at the same time, they must have constancy within the same survey-the same elements of design must win the same marks obtained.
    b
    ) They must be determined as to win the highest multiple correlation coefficient, when they are put into the estimation formula.
    c
    ) They must be reasonable. In order to justify them, we must carry many researches on the actual condition. The frequency of accurence of each grade of
    E
    ,
    F
    values, as the table
    5
    -4, and
    5
    -
    5
    in the thesis in Japanese.
  • Charles-Henri de NOVION, Paul COSTA
    Journal of Nuclear Science and Technology
    1971年 8 巻 10 号 600-601
    発行日: 1971/10/25
    公開日: 2008/12/19
    ジャーナル フリー
  • 堀田 智明, 玉江 忠明, 菅原 真澄, 田中 英二, 坪田 博明, 宮瀬 晴久, 三浦 哲生, 中川 格
    日本物理学会講演概要集. 秋の分科会
    1996年 1996.1 巻 9a-G-5
    発行日: 1996/09/13
    公開日: 2018/03/23
    会議録・要旨集 フリー
  • R.G. WAN, P.J. GUO
    地盤工学会論文報告集
    1999年 39 巻 6 号 1-11
    発行日: 1999/12/15
    公開日: 2008/02/29
    ジャーナル フリー
    This paper outlines a mathematical description of the stress dilatancy behaviour of granular materials which accounts for stress level and void ratio dependencies. The consideration of these aspects has important implications in the modelling of granular material behaviour. In fact, granular material mechanical response is largely dominated by the evolution of dilatancy, fabric and void ratio histories. The starting point in this study is the well established Rowe's theory which is revisited and ultimately modified by introducing a factor linked to governing state parameters in order to describe the complete behaviour of granular materials during deformation. Numerical simulations of triaxial tests on granular materials at different void ratios and stress levels are herein presented to illustrate the model.
  • 斎藤 徹, 井上 勲, 藤井 澄三
    Chemical and Pharmaceutical Bulletin
    1990年 38 巻 6 号 1536-1547
    発行日: 1990/06/25
    公開日: 2008/03/31
    ジャーナル フリー
    A full account is given of the chemical behavior observed for
    7
    ,
    9
    -dialkyladeninium salts (16). On treatment with boiling 1N aqueous NaOH for 60min, 16a,
    b
    , d,
    e
    (X=I), 16
    c
    (X=Br), and 16
    f
    (X=ClO4) rearranged to isomeric N6,
    7
    -dialkyladenines (21a-
    f
    ) in 50-91% yields. Treatment of the salts with
    0
    .
    5
    N aqueous
    Na2CO3
    at room temperature for 30-
    90
    min or with Amberlite CG-400 (OH-) in
    H2O
    at room temperature gave the ring-opened derivatives
    22
    a-
    f
    (in the trans-formamide form) in 56-83% yields, and rate constants for the ring-opening reactions of 16a,
    b
    , d-g (X=ClO4) and 16
    c
    (X=Br) leading to
    22
    a-g were determined in
    H2O
    at pH
    9
    .84 and ionic strength
    0
    .50 at 25°
    C
    . Cyclization of
    22
    a with NaH in
    AcNMe2
    at room temperature or with boiling 1N aqueous NaOH produced 21a in 84% or 72% yield, respectively.In solution, the trans-formamides
    22
    seemed to transform slowly into the cis-formamides 23, attaining equilibria. The existence of such an equilibrium in
    D2O
    or
    Me2SO
    -d6 at 25°
    C
    or in
    H2O
    at pH
    9
    .84 and ionic strength
    0
    .50 at 25°
    C
    was kinetically confirmed in the case of
    22
    a, and the mechanism of the rearrangement of 16 to 21 through
    22
    is discussed on the basis of the above kinetic results and Deslongchamps' theory of stereoelectronic control. On treatment with NaBH4 in MeOH at room temperature, 16a (X=I) furnished the
    7
    , 8-dihydro derivative 28 (84% yield), which slowly decomposed in
    H2O
    at 60°
    C
    to give
    22
    a in 49% yield.The
    7
    ,
    9
    -dialkyladeninium salts (16) were found to be obtainable from N'-alkoxy-1-alkyl-
    5
    -formamidoimidazole-4-carboxamidines (
    9
    ) through an alternative synthetic route : Alkylations of
    9
    with alkyl halides in
    HCONMe2
    in the absence of base, followed by hydrogenolysis of the N'-alkoxy group and cyclizatio (or vice versa) produced 16 in acceptable yields. In order to interpret the proton nuclear magnetic resonance spectrum of
    22
    a, the
    2
    -deuterated species 26 was also synthesized from 24 via 25 and 27.
  • 末次 康将
    マリンエンジニアリング
    2021年 56 巻 5 号 680-687
    発行日: 2021/09/01
    公開日: 2021/10/12
    ジャーナル フリー
  • VINCENZO FIORAVANTE
    地盤工学会論文報告集
    2000年 40 巻 4 号 129-142
    発行日: 2000/08/15
    公開日: 2008/02/29
    ジャーナル フリー
    The small strain stiffness and anisotropic nature of two sands with different geological origin have been determined via laboratory seismic tests performed in a triaxial cell. Dry triaxial reconstituted specimens of Ticino river silica sand (TS) and of Kenya carbonatic sand (KS) were subjected to isotropic and anisotropic states of effective stress ; then both shear and constrained compression waves were propagated in vertical, horizontal and oblique directions by means of five couples of piezoelectric transducers especially arranged in the specimens. The propagated compression and shear waves allow the assessment of the constrained
    M0
    and shear
    G0
    moduli respectively, at very small strains where, as a first approximation many soils can be assumed, from an engineering point of view, to behave as an elastic cross-anisotropic medium with a vertical axis of symmetry. This paper, after a brief description of the novel measuring technique adopted and of the tested materials, summarises the test results and their interpretation in order to separate the effects of the fabric anisotropy from those produced by the state of effective stresses on soil stiffness. The stiffness and anisotropic response of the two tested sands are compared. Finally the results enable us to establish five independent constants of the cross-anisotropic elasticity model, which appears to be appropriate to reproduce the behaviour at small strain of the two sands.
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