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中国でヒトに感染した鳥インフルエンザA(H
7
N
9
) ウイルスの性状，検査系の開発およびワクチン開発とその問題点

小田切孝人, 田代眞人

ウイルス
2013年 63 巻 2 号 233-240
発行日: 2013/12/25
公開日: 2014/10/31

DOI https://doi.org/10.2222/jsv.63.233

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Syntheses of
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-Octahydro-11-oxodibenz [
b
,
e
] oxepins and
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-Octahydro-11-oxodibenzo [
b
,
e
] thiepins

黒川美貴雄, 吉田耕治, 永井保嵩, 宇野準

Chemical and Pharmaceutical Bulletin
1983年 31 巻 12 号 4312-4318
発行日: 1983/12/25
公開日: 2008/03/31

DOI https://doi.org/10.1248/cpb.31.4312

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Two new partially saturated tricyclic ring systems,
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-octahydro-11-oxodibenz [
b
,
e
] oxepins (3a and 3
b
), and -thiepins (
4
a and
4
b
) were synthesized. Compounds
4
a and
4
b
were desulfurized to give a pair of isomeric 2-methylbenzoylcyclohexanes (10a and 10
b
). Deuterated
4
a and
4
b
(11a and 11
b
) were prepared starting from butadiene-
d₆
(12). The stereochemical features of 3a (trans), 3
b
(cis),
4
a (trans) and
4
b
(cis) are compared with those of 10a, 10
b
, 11a and 11
b
on the basis of proton nuclear magnetic resonance data.
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Sythesis and Stereochemistry of 11-Amino-
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-octahydrodibenzo[
b
,
e
]thiepines and-oxepines

黒川美貴雄, 糸川彰, 松本純一, 福本吉久, 月原冨武

Chemical and Pharmaceutical Bulletin
1992年 40 巻 9 号 2270-2274
発行日: 1992/09/25
公開日: 2008/03/31

DOI https://doi.org/10.1248/cpb.40.2270

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11-Amino-
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-octahydrodibebenzo[
b
,
e
]thiepines (
6
a-d) and -oxepines (
7
a-d) were synthesized by the Leuckart reaction of
6
,
6
a,
7
,
8
,
9
, 10, 10a, 11-octahydro-11-oxodibenzo[
b
,
e
]thiepines (1a,
b
)and -oxepines (2a,
b
) followed by hydrolysis of the reaction products
4
a-d and
5
a-d, respectively. The four diastereomers, cis(
6
a-H, 10a-H)-cis(10a-H, 11-H)
6
a and
7
a, cis(
6
a-H, 10a-H)-trans(10a-H, 11-H)
6
b
and
7
b
, trans(
6
a-H, 10a-H)-trans(10a-H, 11a-H)
6
c
and
7
c
, and trans(
6
a-H, 10a-H)-cis(10a-H, 11-H)
6
d and
7
d, were isolated and their configurations and conformations were elucidated by chemical methods together with ¹H-nuclear magnetic resonance spectroscopic and X-ray crystallographic analyses.
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より実用的な飛行機への探求

Grover Loening

日本航空学会誌
1963年 11 巻 119 号 373-380
発行日: 1963年
公開日: 2009/05/25

DOI https://doi.org/10.2322/jjsass1953.11.373

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The Japan Connection

Nicholas ISYUMOV, Eric HO, Peter KING, David SURRY, Barry VICKERY

日本風工学会誌
2010年 35 巻 4 号 265-271
発行日: 2010/10/31
公開日: 2011/04/01

DOI https://doi.org/10.5359/jawe.35.265

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BINDING OF TOBRAMYCIN TO ESCHERICHIA COLI RIBOSOMES: CHARACTERISTICS AND EQUILIBRIUM OF THE REACTION

FRANÇOIS LE GOFFIC, FRÉDÉRIC TANGY, BERNARD MOREAU

The Journal of Antibiotics
1979年 32 巻 12 号 1288-1292
発行日: 1979年
公開日: 2006/04/12

DOI https://doi.org/10.7164/antibiotics.32.1288

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A sample of [³H] tobrarnycin (
5
, 000 Ci/Mole) has been synthetized and incubated with
the bacterial ribosome and its subunits. The results obtained show that this antibiotic has
two types of binding sites. The primary one is probably responsible for the inhibition of
protein synthesis whereas the secondary one is probably related to the misreading and reading
tiirough of the messenger RNA.
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英国における過去半世紀 (1922～1972) 間の冶金用コークスの研究

George W. Lee

燃料協会誌
1973年 52 巻 3 号 171-177
発行日: 1973/03/20
公開日: 2010/06/28

DOI https://doi.org/10.3775/jie.52.171

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MICROSEISM BARRIERS

M. L. GHOSH

Journal of Physics of the Earth
1972年 20 巻 2 号 165-186
発行日: 1972年
公開日: 2009/04/30

DOI https://doi.org/10.4294/jpe1952.20.165

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The possibility of attenuation of microseismic waves due to the presence of an upward folding of the ocean bottom into the liquid is discussed in this paper. The upward folding of the ocean bottom has been idealized by means of an irregularity in the form of a rectangle intruding into the liquid and the evaluation of the displacement component at any point of the solid medium has been carried out in two stages. First, the change in the incident mode of the surface wave due to the presence of the rectangular irregularity has been determined, and second, the subsequent change of the resulting displacement components due to the termination of the liquid layer and the step change in elevation of the solid medium at the continental margin has been discovered. Finally, numerical calculation has been made to determine the attenuation of the microseismic waves of different periods due to the presence of the rectangular irregularity at the ocean bottom.
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STEREOSELECTIVE ALDOL REACTION OF A LITHIUM α-VINYL ENOLATE TO α-ALKOXY ALDEHYDES

井原正隆, 千尋正利, 福本圭一郎, 亀谷哲治

Chemical and Pharmaceutical Bulletin
1984年 32 巻 1 号 373-376
発行日: 1984/01/25
公開日: 2008/03/31

DOI https://doi.org/10.1248/cpb.32.373

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Stereoselective synthesis of the
4
,
5
-syn,
5
,
6
-anti adducts (14 and 16) on the aldol condensation of the Z (O)-lithium enolate, derived from the
E
-enone (2), to α-alkoxy aldehydes (12 and 13) was proved via the successive intramolecular Diels-Alder reaction.
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カナダにおける製紙原料供給の現状

増大する資源

E
. F. Boswell

紙パ技協誌
1998年 52 巻 7 号 885-889
発行日: 1998/07/01
公開日: 2009/11/19

DOI https://doi.org/10.2524/jtappij.52.885

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The world is in the midst of a huge fundamental shift in fibre supply, demand balances, and policy changes. Governments around the world are introducing policy changes which influence the supply demand balance as the politicians' thoughts are uttered. Government agencies and their bureaucrats are imposing changes on industry even before the legislation is passed by the government in question.
This ad hoc change process will continue for a time to come until the countries in question show a tough-mindedness with regard to their land use policies. Policies affecting forest areas such as protection areas, Native land claims, the protection of biodiversity and a true goal of sustainable development ; which addresses the combined issues of cultural, environmental, social and economic matters.
Eventually all of these difficult issues will reach essential closure. Then there will be great new opportunities for investment to meet the growing demand for forest products ; leading to a strengthening competitive position in the more traditional producing areas such as Canada.
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Alcaloides de Caryomene olivascens. : Nouvelles Structures Bisbenzylisoquinoleiques

MARIE LAVAULT, ALAIN FOURNET, HELENE GUINAUDEAU, JEAN BRUNETON

Chemical and Pharmaceutical Bulletin
1986年 34 巻 3 号 1148-1152
発行日: 1986/03/25
公開日: 2008/03/31

DOI https://doi.org/10.1248/cpb.34.1148

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Nine isoquinoline alkaloids belonging to the protoberberine, proaporphine and bisbenzyl-isoquinoline series were isolated from Caryomene olivascens (Menispermaceae). Four compounds are new : (-)-2-norlimacine (
4
), (-)-caryolivine (
6
), (+)-1, 2-dehydro-2-norlimacusine (
9
) and N-formylstepharine (3). The last one is the first N-formyl derivative to be reported in the proaporphine group. Its biogenetic origin is discussed. Structures were established on the basis of 360 MHz (FT) nuclear magnetic resonance measurements and also by chemical correlation in the case of 3.
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熱力学諸量の測定とその結果を用いた化学熱力学計算によるNi-Mo-
B
およびNi-W-
B
3成分系状態図の決定

香山滉一郎, 森下政夫, 張国鋒

粉体および粉末冶金
2006年 53 巻 5 号 419-429
発行日: 2006年
公開日: 2006/12/19

DOI https://doi.org/10.2497/jjspm.53.419

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The phase diagrams of the Ni-Mo-
B
and Ni-W-
B
ternary systems in the region of less than 50mol%
B
were constructed by thermodynamic calculation, based on the data obtained by thermodynamic measurement of the related materials. We found three ternary eutectic points and three or two ternary peritecto-eutectic points as follows:
E₁
:L (1365K, 71.
5
mol%Ni-
6
.
0
mol%Mo-
22
.
5
mol%
B
)=(Ni)+
Ni₃B
+
NiMo₂B₂

E₂
:L (1355K, 62.
5
mol%Ni-2.
5
mol%Mo-30.
5
mol%
B
)=
Ni₃B
+
Ni₂B
+
NiMo₂B₂

E₃
:L (1445K, 42.
0
mol%Ni-30.
6
mol%Mo-10.3mol%
B
)=(Ni)+NiMo+
NiMo₂B₂

P₁:L (1812K, 34.
9
mol%Ni-42.3mol%Mo-
22
.
8
mol%
B
)+MoB=
Mo₂B
+
NiMo₂B₂

P₂:L (1633K, 42.3mol%Ni-40.
4
mol%Mo-17.3mol%
B
)+Mo=
Mo₂B
+
NiMo₂B₂

P₃:L (1812K, 53.
5
mol%Ni-33.
7
mol%Mo-12.
8
mol%
B
)+Mo=NiMo+
NiMo₂B₂

E₁
:L (1622K, 51.
0
mol%Ni-31.
6
mol%W-17.
4
mol%
B
)=(Ni)+W+
NiW₂B₂

E₂
:L (1260K, 71.
0
mol%Ni-
7
.
0
mol%W-
22
.
0
mol%
B
)=(Ni)+
Ni₃B
+
NiW₂B₂

E₃
:L (1291K, 65.
4
mol%Ni-
4
.
8
mol%W-29.
8
mol%
B
)=
Ni₂B
+
Ni₃B
+
NiW₂B₂

P₁:L (2115K, 23.
8
mol%Ni-43.1mol%W-33.1mol%
B
)+WB=
W₂B
+
NiW₂B₂

P₂:L (1657K, 48.
9
mol%Ni-33.1mol%W-18.
0
mol%
B
)+
W₂B
=W+
NiW₂B₂

The calculated phase diagrams are expected to be useful for the development of new Ni-based heat-, corrosion- or wear-resistance alloys.
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Lighting Hardware

I. F. Davies

Journal of Light & Visual Environment
1984年 8 巻 1 号 1_9-1_20
発行日: 1984年
公開日: 2011/05/20

DOI https://doi.org/10.2150/jlve.8.1_9

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Role of Vitamins
C
and
E
in Regulating Antioxidant and Pro-Oxidant Markers in Preeclampsia

Mohd Suhail, Mohd Faizul Suhail, Hina Khan

Journal of Clinical Biochemistry and Nutrition
2008年 43 巻 3 号 210-220
発行日: 2008年
公開日: 2008/10/31

DOI https://doi.org/10.3164/jcbn.2008067

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We compared three groups of pregnant women: placebo with normotensive women, group A which included preeclamptics, and group
B
which comprised preeclamptics who were supplemented their diets with vitamins
C
and
E
. MDA increased from
6
.
22
± 2.
8
(placebo) to
8
.48 ± 1.2 (A) and
8
.02 ± 1.
8
nmol/gHb (
B
). NO concentrations were enhanced from 19.3 ±
4
.2 (P) to 23.
8
±
6
.
4
(A) and 24.1 ±
5
.
4
μmol/L (
B
). GSH contents were decreased from 10.42 ± 2.81 (P) to
8
.02 ± 2.92 (A) and
9
.39 ± 1.02 μmol/g Hb (
B
), whereas GSSG concentrations increased from
0
.98 ±
0
.28 (P) to 1.24 ±
0
.29 (A) and 1.08 ±
0
.12 μmol/g Hb (
B
). SOD activity decreased 23% in A and 14% in
B
; GRx decreased 27% in A and
5
.
5
% in
B
; GPx decreased 12% in A and
9
.
6
% in
B
. Catalase activity, however, increased 27% in A and 29% in
B
as compared to control. Thus, we conclude that the use of vitamins
C
and
E
should be considered for the control of certain important biochemical indices during the development of preeclampsia; however, further studies are needed to develop methods for the prevention of preeclampsia in women at high risk.

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竺道生の涅槃思想-その序説-

張曼濤

印度學佛教學研究
1967年 15 巻 2 号 650-652
発行日: 1967/03/31
公開日: 2010/03/09

DOI https://doi.org/10.4259/ibk.15.650

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Petri Neural Network Model for the Effect of Controlled Thermomechanical Process Parameters on the Mechanical Properties of HSLA Steels

S. Datta, J. Sil, M. K. Banerjee

ISIJ International
1999年 39 巻 10 号 986-990
発行日: 1999/10/15
公開日: 2007/05/31

DOI https://doi.org/10.2355/isijinternational.39.986

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The effect of composition and controlled thermomechanical process parameters on the mechanical properties of HSLA steels is modelled using the Widrow-Hoff's concept of training a neural net with feed-forward topology by applying Rumelhart's back propagation type algorithm for supervised learning, using a Petri like net structure. The data used are from laboratory experiments as well as from the published literature. The results from the neural network are found to be consistent and in good agreement with the experimented results.
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地盤数値情報データベースを用いた熊本県中部域斜面災害の解析

田尻要, 中山洋, 今泉繁良

土質工学会論文報告集
1992年 32 巻 2 号 159-168
発行日: 1992/06/15
公開日: 2008/02/29

DOI https://doi.org/10.3208/sandf1972.32.2_159

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The production of nematode-immobilizing secretory cells by Climacodon septentrionalis

Joey
B
. Tanney, Leonard J. Hutchison

Mycoscience
2012年 53 巻 1 号 31-35
発行日: 2012年
公開日: 2023/03/31

DOI https://doi.org/10.1007/s10267-011-0128-1

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The ability of Climacodon septentrionalis to immobilize and kill a mycophagous nematode (Aphelenchoides sp.) in vitro is described for the first time. Two isolates produced droplets (20–45 μm in diameter) that formed at the apices of tall, stalked, and branching secretory cells (700–1,500 μm tall). On 2% modified malt extract agar, nematodes became enveloped in the droplets, which restricted their ability to move and resulted in complete immobilization and death within several hours of contact. The rate of decomposition of the nematodes varied considerably, with most individuals persisting for weeks whereas others were degraded within several days and appeared to be colonized by dense hyphal growth. This study provides the first documentation of a non-agaricoid fungus producing secretory cells that are able to immobilize nematodes.

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虚血性心臟病におけるコレステロール負荷時の血清リポ蛋白変動(第2報)

―特にアポ蛋白Eの変化について―

本間康彦, 三神美和, 佐藤美智子, 石原仁一, 吉川広, 木下栄治, 田川隆介, 星合充基, 古屋秀夫, 井出満, 田辺晃久, 玉地寛光, 兼本成斌, 友田春夫, 中谷矩章, 五島雄一郎

動脈硬化
1984年 12 巻 3 号 599-603
発行日: 1984/08/01
公開日: 2011/09/21

DOI https://doi.org/10.5551/jat1973.12.3_599

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Seven hundred fifty mg of cholesterol were fed daily to 32 patients of the ischemic heart disease (IHD) for 2 weeks. Cholesterol amounts in VLDL, LDL, HDL, HDL₂ and HDL₃ were estimated on the
0
th,
7
th and 14th days of cholesterol load. Plasma apoprotein A-I, A-II,
B
,
C
-II,
E
levels were also measured in 16 from 32 IHD subjects. Apoprotein levels were estimated by a method of single radial immunodiffusion (SRID). Before cholesterol administration, cholesterol amounts in VLDL, LDL, HDL, HDL₂ and HDL₃ were 15.
9
±
7
.
5
mg/dl (mean±SD), 150.
9
±58.1mg/dl 43.
8
±
9
.
6
mg/dl, 16.
4
±
5
.
8
mg/dl and 24.
9
±
6
.3mg/dl respectively. Plasma apoprotein A-I, A-II,
B
,
C
-II and
E
levels were 81.
7
±
22
.
0
mg/dl, 15.1±
5
.
4
mg/dl, 93.
7
±36.
0
mg/dl, 3.83±1.00mg/dl and
4
.29±1.36mg/dl respectively. After 2 weeks' cholesterol feeding, all plasma lipoprotein cholesterol and apoprotein levels did not change significantly. Correlation coefficients between plasma apoprotein and lipoprotein cholesterol levels were calculated. Apoprotein A-I and A-II correlated with HDL-
C
(r=
0
.348), HDL₂-
C
(r=
0
.612) and HDL₃ (r=
0
.569). Apoprotein
B
correlated with total cholesterol (TC) (r=
0
.610), VLDL-
C
(r=
0
.341), LDL-
C
(r=
0
.726), HDL-
C
(r=
0
.432) and HDL₂-
C
(r=
0
.465). Apoprotein
C
-II correlated with TC (r=
0
.765), TG (r=
0
.679), VLDL-
C
(r=
0
.651), LDL-
C
(r=
0
.461) and HDL₂-
C
(r=
0
.326). Apoprotein
E
correlated with TC (r=
0
.580), TG (r=
0
.575) and VLDL-
C
(r=
0
.666). Interapoprotein's correlations were also calculated. Apoprotein A-I correlated with apoprotein A-II (r=
0
.468). Apoprotein
B
correlated with apoprotein
C
-II (r=
0
.393). Apoprotein
C
-II correlated with apoprotein
B
(r=
0
.393) and
E
(r=
0
.549). Apoprotein
E
only correlated with apoprotein
C
-II (r=
0
.549).
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最新ドイツ・
E
.
C
. H. Will社平判シーターモデル “GFS”

福元葵, K. Sumfleth

紙パ技協誌
2002年 56 巻 11 号 1598-1601
発行日: 2002/11/01
公開日: 2009/11/19

DOI https://doi.org/10.2524/jtappij.56.1598

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Since 135 years
E.C
.H.Will Hamburg is one of the leading manufacturers of converting machinery for the paper industry.The company has gained worldwide acknowledgement when introducing cut size sheeters for copy paper. These machines are used worldwide by all well-known paper makers and also in the meantime by smaller paper converting companies.
With regard to folio size sheeter
E.C
.H.Will was and is reknown for special solutions instead. Based on and with the knowhow of hundreds of cut size sheeters and some hundred folio size sheeters having been delivered, the concept of the Will “global folio size sheeter” type GFS has been developed.
The great technical experience in cutting and transporting paper as well as introducing innovative ideas, new materials and, last but not least, the influence of various customers' requests, which are known to
E.C
.H.Will from numerous special projects, were the base for development of the GFS folio sheeter.
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