1988 年 21 巻 4 号 p. 383-387
Noradrenaline levels and distribution in different components of rat knee joint were studied using radioenzymatic assay and glyoxylic acid histofluorescence techniques.
The articular capsule possessed the highest noradrenaline content, and the levels of noradrenaline in cruciate ligaments were slightly higher than in collateral ligaments. In all joint components, noradrenergic nerve fibres were associated almost exclusively with the blood vessels.
The possible involvement of a noradrenergic action on joint microcirculation in the pathophysiology of rheumatoid arthritis is discussed.