Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Sciences and Technology, Huazhong University of Science and Technology
Moctar Ali CHAIBOU
Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Sciences and Technology, Huazhong University of Science and Technology
Zhengwang CHEN
Key Laboratory of Molecular Biophysics of the Ministry of Education, College of Life Sciences and Technology, Huazhong University of Science and Technology
Our previous studies revealed that daintain/AIF-1 promoted the proliferation and migration of breast cancer cells. In the present study, we investigated the effect of daintain/AIF-1 on the cisplatin resistance of breast cancer cells. The results indicated that daintain/AIF-1 reinforced the resistance of breast cancer cells to cisplatin by inhibition of cell apoptosis and reduction of intracellular cisplatin accumulation.
