Bioscience, Biotechnology, and Biochemistry
Online ISSN : 1347-6947
Print ISSN : 0916-8451
Organic Chemistry Notes
Biosynthesis of Coumarin Glycosides by Transgenic Hairy Roots of Polygonum multiflorum
Liangbin ZHOU, Tian TIAN, Bailin XUE, Liyan SONG, Ling LIU, Rongmin YU
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2012 年 76 巻 5 号 p. 1008-1010

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To investigate the substrate specificity and regio-selectivity of coumarin glycosyltransferases in transgenic hairy roots of Polygonum multiflorum, esculetin (1) and eight hydroxycoumarins (2–9) were employed as substrates. Nine corresponding glycosides (10–18) involving four new compounds, 6-chloro-4-methylcoumarin 7-O-β-D-glucopyranoside (15), 6-chloro-4-phenylcoumarin 7-O-β-D-glucopyranoside (16), 8-hydroxy-4-methylcoumarin 7-O-β-D-glucopyranoside (17), and 8-allyl-4-methylcoumarin 7-O-β-D-glucopyranoside (18), were biosynthesized by the hairy roots.
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© 2012 by Japan Society for Bioscience, Biotechnology, and Agrochemistry
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