Chiisanoside Is Not Absorbed but Inhibits Oil Absorption in the Small Intestine of Rodents

Kazuma YOSHIZUMI; Kaeko MUROTA; Shiro WATANABE; Hironori TOMI; Tomoko TSUJI; Junji TERAO

doi:10.1271/bbb.70761

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Chiisanoside Is Not Absorbed but Inhibits Oil Absorption in the Small Intestine of Rodents

Kazuma YOSHIZUMI, Kaeko MUROTA, Shiro WATANABE, Hironori TOMI, Tomoko TSUJI, Junji TERAO

著者情報

キーワード: chiisanoside, 3, 4-seco-lupane triterpenoid saponin, Acanthopanax sessiliflorus, lipase inhibitor, intestinal absorption

ジャーナルフリー早期公開

論文ID: 70761

DOI https://doi.org/10.1271/bbb.70761

この記事には本公開記事があります。

The final version of this article is now available: Vol. 72 (2008) , No. 4 p.1126

詳細

抄録

Chiisanoside is the main component of Acanthopanax sessiliflorus leaves. Simultaneous administration of chiisanoside resulted in a decrease in the plasma TG level and increase of undigested TG in the intestinal lumen after oil gavage to mice. This suggests that chiisanoside has the potential to prevent obesity as a lipase inhibitor which suppresses fat absorption in vivo.

責任著者(Corresponding author)

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