抄録
Alkyl esters of p-hydroxybenzoic acid rapidly transfer from the medium to the yeast cell, and the transferred ester is accumulated in the cell. The transfer ratio of the ester increases as the alkyl radical becomes higher, and also, its toxic effect on the yeast increases in the same manner.
In this case, a part of the transferred ester is adsorbed on the solid phase of the cell and the other part is dissolved in the lipid phase and in the inner cell fluid. When the alkyl radical of the ester is changed, it is observed that a definite quantity of the adsorbed ester is required in order to give a definite inhibiting effect on the yeast growth, though the concentration of the dissolved ester in the lipid phase and in the inner cell fluid changes. Accordingly, it is concluded that the toxic effect mainly depends upon the adsorbed esters, being independent of the dissolved ester in the lipid phase or in the inner cell fluid.
