Biological and Pharmaceutical Bulletin
Online ISSN : 1347-5215
Print ISSN : 0918-6158
ISSN-L : 0918-6158
A Glucan Having Reticuloendothelial System-Potentiating and Anti-complementary Activities from the Tuber of Pinellia ternata
友田 正司権田 良子大原 直子清水 訓子宍戸 千穂藤木 結花
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1994 年 17 巻 6 号 p. 859-861

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A glucan, called pinellian G, was isolated from the tuber of Pinellia ternata BREIT. It was homogeneous on electrophoresis and gel chromatography, and its molecular mass was westimated to be 1.5×104. It is composed solely of D-glucose, in addition to a few O-acetyl groups. Methylation analysis, nuclear magnetic resonance and enzymic degradation studies indicated that it is a branched glucan mainly composed of α-1, 4-linked D-glucopyranose residues with partially α-1, 3-linked units and 4, 6-branching points. The glucan showed significant reticuloendothelial system-potentiating activity in a carbon clearance test, as well as pronounced anti-complementary activity.
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© The Pharmaceutical Society of Japan
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