Prehospital Vital Signs, Including SpO2, Are Significantly Associated With Mortality and Mechanical Circulatory Support Requirement in Acute Myocardial Infarction Patients

Tairo Kurita; Yumi Hirota; Hiroki Mori; Yosuke Kirii; Hiromasa Ito; Akihoro Takasaki; Keishi Moriwaki; Takeshi Takamura; Kozo Hoshino; Takashi Tanigawa; Tetsuya Kitamura; Norikazu Yamada; Kaoru Dohi

doi:10.1253/circj.CJ-25-0584

Research Letter

Prehospital Vital Signs, Including SpO₂, Are Significantly Associated With Mortality and Mechanical Circulatory Support Requirement in Acute Myocardial Infarction Patients

Tairo Kurita , Yumi Hirota, Hiroki Mori, Yosuke Kirii, Hiromasa Ito, Akihoro Takasaki, Keishi Moriwaki, Takeshi Takamura, Kozo Hoshino, Takashi Tanigawa, Tetsuya Kitamura, Norikazu Yamada, Kaoru Dohi

著者情報

キーワード: Acute myocardial infarction (AMI), Oxygen saturation, Prehospital vital signs, Risk stratification

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2025 年 89 巻 11 号 p. 1833-1835

DOI https://doi.org/10.1253/circj.CJ-25-0584

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Background: Early risk stratification for acute myocardial infarction (AMI) using prehospital vital signs, including percutaneous oxygen before oxygen supply (pre-SpO₂), remains underexplored.

Methods and Results: We analyzed 3,006 AMI patients from the Mie ACS Registry. Patients were stratified by the prehospital Simple Risk Index (pre-SRI = [heart rate × (age / 10)²] / systolic blood pressure) and pre-SpO₂levels. The primary outcome was 30-day death. Combined assessment of pre-SRI and pre-SpO₂was superior to individual parameters for predicting 30-day death. In the multivariate analysis, combined assessment (SRI ≥34 and SpO₂≤94%) was the strongest independent predictors of 30-day death (hazard ratio 3.98, P<0.001).

Conclusions: Prehospital vital signs including pre-SpO₂enable early high-risk identification, improving clinical decision-making for hospital selection.

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