Clinical Characteristics and Outcomes of Infective Endocarditis in Patients Undergoing Maintenance Hemodialysis　― A Retrospective Nationwide Database Analysis ―

Kyo Kamisaka; Hiroshi Okamoto; Takeshi Nishi; Yoshitaka Sasahira; Koshiro Kanaoka; Yoko Sumita; Chisato Izumi; Shiro Uemura

doi:10.1253/circj.CJ-25-0646

Kyo Kamisaka, Hiroshi Okamoto, Takeshi Nishi, Yoshitaka Sasahira, Koshiro Kanaoka, Yoko Sumita, Chisato Izumi, Shiro Uemura

著者情報

キーワード: In-hospital mortality, Infective endocarditis, Maintenance hemodialysis

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論文ID: CJ-25-0646

DOI https://doi.org/10.1253/circj.CJ-25-0646

詳細

抄録

Background: Patients with infective endocarditis (IE) on maintenance hemodialysis (HD) have poor outcomes, but contemporary data remain limited.

Methods and Results: We conducted a retrospective analysis using a nationwide Japanese administrative database and identified 12,158 patients hospitalized with IE between 2018 and 2021, including 806 (6.6%) on maintenance HD. The inhospital mortality rate was significantly higher in HD patients (30.0% vs. 13.5%, P<0.05).

Conclusions: Maintenance HD patients with IE had worse outcomes, underscoring the need for early recognition and tailored management in this highrisk group.

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