Cough Investigation
Online ISSN : 2759-6087
原著
メントール口腔内刺激による鎮咳効果の検討
片山 伸幸西木 一哲中村 暁子
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ジャーナル オープンアクセス

2025 年 2 巻 p. 21-24

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Background: Menthol is an ingredient with antitussive properties in over-the-counter medicines. However, only a few studies support the cough-relieving effects of these products. Therefore, we aimed to examine the cough-relieving effects of menthol. Methods: Baseline capsaicin cough sensitivity was measured in healthy adults on day one. Four weeks later, the menthol oral stimulation test was performed. Results: Forty-four individuals participated in this study. Median capsaicin threshold concentration of control and menthol were 7.81 μM and 15.63 μM, respectively. Cough thresholds were increased by oral menthol stimulation. Conclusions: Oral administration of menthol suppressed capsaicin cough sensitivity in healthy adults.

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