Chemistry of Renieramycins. Part 4. Synthesis of a Simple Natural Marine Product, 6-Hydroxy-7-methoxyisoquinolinemethanol

Naoki Saito; Chieko Tanaka; Tomoo Satomi; Chigusa Oyama; Akinori Kubo

doi:10.1248/cpb.52.282

Notes

Chemistry of Renieramycins. Part 4.
Synthesis of a Simple Natural Marine Product, 6-Hydroxy-7-methoxyisoquinolinemethanol

Naoki Saito, Chieko Tanaka, Tomoo Satomi, Chigusa Oyama, Akinori Kubo

著者情報

キーワード: Pomeranz–Fritsch synthesis, phenol, marine natural product, isoquinoline, isopropyl protecting group

ジャーナルフリー

2004 年 52 巻 2 号 p. 282-286

DOI https://doi.org/10.1248/cpb.52.282

詳細

抄録

6-Hydroxy-7-methoxyisoquinolinemethanol (15) and mimosamycin (1) were recently isolated from a marine sponge, Haliclona sp. The former was prepared in ten steps from vanillin (22) in 26% overall yield using an isopropyl for phenol protection.

責任著者(Corresponding author)

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