Chemical and Pharmaceutical Bulletin
Online ISSN : 1347-5223
Print ISSN : 0009-2363
ISSN-L : 0009-2363
Notes
Synthesis of New Galβ1→4Fuc Segments Useful for Biological Investigations
Kazusa NishiyamaAtsushi YamadaTomoharu TakeuchiYoichiro ArataKen-ichi KasaiTetsuta OshitariHideaki NatsugariHideyo Takahashi
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2011 Volume 59 Issue 10 Pages 1307-1310

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Abstract
Useful segments (1, 2) for chemical probes embedded in a Galβ1→4Fuc unit were designed and prepared for characterizing sugar-binding proteins in Caenorhabditis elegans. Segment 1 with an amino group terminus was used as a recognition unit in affinity chromatography. It was revealed that some proteins (annexins and galectins) in C. elegans have an affinity for Galβ1→4Fuc.
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© 2011 The Pharmaceutical Society of Japan
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