Atypical Cyclic Sulfides, Garlicnins G, I, and J, Extracted from Allium sativum

Masateru Ono; Yukio Fujiwara; Tsuyoshi Ikeda; Cheng Pan; Mona El-Aasr; Jong-Hyun Lee; Daisuke Nakano; Junei Kinjo; Toshihiro Nohara

doi:10.1248/cpb.c16-00648

Notes

Atypical Cyclic Sulfides, Garlicnins G, I, and J, Extracted from Allium sativum

Masateru Ono, Yukio Fujiwara, Tsuyoshi Ikeda, Cheng Pan, Mona El-Aasr, Jong-Hyun Lee, Daisuke Nakano, Junei Kinjo, Toshihiro Nohara

Author information

Masateru Ono
School of Agriculture, Tokai University
Yukio Fujiwara
Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University
Tsuyoshi Ikeda
Faculty of Pharmaceutical Sciences, Sojo University
Cheng Pan
Graduate School of Medical Sciences, Faculty of Life Sciences, Kumamoto University
Mona El-Aasr
Faculty of Pharmacy, Tanta University
Jong-Hyun Lee
College of Pharmacy, Dongduk Women’s University
Daisuke Nakano
Faculty of Pharmaceutical Sciences, Fukuoka University
Junei Kinjo
Faculty of Pharmaceutical Sciences, Fukuoka University
Toshihiro Nohara Corresponding author
Faculty of Pharmaceutical Sciences, Sojo University

Keywords: Allium sativum, atypical sulfide, cyclic sulfoxide, garlicnin G, garlicnin I, garlicnin J

JOURNAL FREE ACCESS FULL-TEXT HTML

2017 Volume 65 Issue 1 Pages 102-106

DOI https://doi.org/10.1248/cpb.c16-00648

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Abstract

Newly characterized, atypical sulfides, garlicnins G (1), I (2), and J (3), were isolated from the acetone extracts of garlic bulbs, Allium sativum. Their production pathways are regarded as different from those of cyclic sulfoxides, 3,4-dimethyltetrahydrothiophene-S-oxide derivatives such as onionins A₁–A₃, garlicnins B₁–B₄ and C₁–C₃.

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