Studies on the Synthesis of New Antimicrobials. I. Synthesis of 2, 5-Dichloroaniline Derivatives and their Some Antibacterial Activities

Abstract

Twentyfour of new N-derivatives of 2, 5-dichloroaniline, 2, 5-dichloro-4-bromo-aniline and 2, 5-dichloro-4-thiocyanatoaniline were synthesized in order to investigate the potential antimicrobial activity. Among them, 2-hydroxy-5-bromobenzoyl derivatives were found to give strong antibacterial activities on Staph. aureus in vitro.